Separation & Purification

DISPATCHES FROM INTERPHEX

So far, so very good: Pall and ATMI talk integration at interphex

21-Mar-2014 By Dan Stanton

While there will always be space for stainless steel systems, single-use technology is now mainstream according to Pall and ATMI.

DISPATCHES FROM INTERPHEX

To QbD or not to QbD? For biologics it's a must says Cook Pharmica expert

19-Mar-2014 By Dan Stanton

The thorny issue of applying QbD to biopharmaceutical manufacture is a topic of hot debate at Interphex 2014 according to CMO Cook Pharmica.

Start spreading the news, Interphex opens today

18-Mar-2014

When Frank Sinatra sang "If you can make it there, you can make it anywhere" in New York, New York he probably wasn't talking about biopharmaceutical production.

Novo Nordisk invests $100m in diabetes pipeline purification plant

18-Mar-2014 By Dan Stanton

Novo Nordisk has invested 550m Danish Kroner ($100m) to expand a purification plant in Denmark for its diabetes biodrug pipeline.

Bayer invests $700m in recombinant Factor VIII manufacturing

12-Mar-2014 By Dan Stanton

Bayer is investing over €500m ($700m) in manufacturing recombinant factor VIII (rFVIII) products citing growing demand for long-term prophylactic treatment rather than ‘on-demand’ haemophilia drugs.

Daiichi’s downstream setback cuts Japanese H5N1 vaccine supplies

12-Mar-2014 By Gareth Macdonald

Less H5N1 influenza vaccine than expected will be available in Japan this year after downstream processing problems at a plant being set up by Daiichi Sankyo.

EU awards CureVac EUR2m for room temp stable mRNA vaccine development

11-Mar-2014 By Gareth Macdonald

CureVac has been awarded a grant by the European Commission (EC), which says the firm's room temperature-stable mRNA-based vaccines could overcome one of the biggest barriers to disease prevention in developing countries.

AB Sciex begins offering ‘breakthrough’ upstream processing tech

05-Mar-2014 By Zachary Brennan

AB Sciex has launched what it claims is the first commercially available ultra-low flow electrospray ionization instrument that links CE (capillary electrophoresis) technology to mass spectrometry.

Immunomedics: mAb massing method buffers against biosimilars

04-Mar-2014 By Gareth Macdonald

Immunomedics claims a new concentration technique has protected its portfolio of candidate mAb cancer drugs from biosimilar competition for longer.

Pall: Single-use skyrockets but stainless steel still shines

28-Feb-2014 By Dan Stanton

Uptake in single-use is “off the charts” but there is still a growing market for traditional stainless steel technology, says Pall following its acquisition of ATMI.

Thermo: SDS Page price cuts in keeping with China's 5-year plan

06-Feb-2014 By Gareth Macdonald

Thermo Fisher Scientific has confirmed that the price cuts imposed by Chinese M&A authorities are part of the country’s efforts to become and biopharmaceutical hub.

Life Tech takeover gives Thermo 'leading brands' says analyst

04-Feb-2014 By Gareth Macdonald

Thermo Fisher Scientific completed its takeover of Life Technologies last night, just two days after the US Federal Trade Commission (FTC) approved the $13.6bn deal.

Thermo Fisher: 'Life begins in February,' as it awaits FTC approval

31-Jan-2014 By Dan Stanton

Thermo Fisher has predicted its $13.6bn takeover of Life Technologies will be completed in February as it reports strong FY 2013 results.

Pall CEO: ATMI deal doesn't rule out other acquisitions

21-Jan-2014 By Dan Stanton

Buying ATMI will help Pall fill gaps in its up and downstream biomanufacturing tech offerings but the deal does not rule out other acquisitions says CEO, Larry Kingsley

Benchtop mass spec tech could offset low biopharma demand for Waters

15-Jan-2014 By Dan Stanton

Subdued demand from Biopharma for its chromatography equipment could be reversed by its benchtop mass spectrometry technology, Waters says.

HyClone units to keep Utah and Colorado HQs says GE Healthcare

08-Jan-2014 By Gareth Macdonald

GE Healthcare has confirmed it will continue to run the HyClone units it is buying from Thermo Fisher Scientific from their existing US bases.

Therapure acquires chromatography tech in Upfront deal

06-Dec-2013 By Dan Stanton

Technology firm Upfront Chromatography has exited the biopharmaceutical manufacturing market after selling its protein purification business to Therapure Biopharma.

GE launches compact automated purification system

27-Nov-2013 By Dan Stanton

GE Healthcare has launched an automated protein purification system it says can save researchers and labs time and decrease the risk of manual error.

IBM's new hydrogel tech uses shear to make mAb delivery less stressful

06-Nov-2013 By Gareth Macdonald

A new vitamin E-based hydrogel technology could improve how cancer busting mAbs are delivered and help biopharmas cut costs according to developer IBM.

Repligen ups disposable chromatography column capacity

06-Nov-2013 By Zachary Brennan

US biopharma company Repligen has completed a 9,000 square foot expansion of its facilities in Massachusetts to meet growing customer demand for disposable chromatography columns and warehousing.

DSM's cGMP biologics plant a boon to Australian biotech, firm says

30-Oct-2013 By Dan Stanton

DSM says its new biomanufacturing facility will benefit the Australian biotech sector, overcoming the problems of distance with foreign contract manufacturers.

UPDATE

Genzyme to strengthen Fabrazyme production with $80m downstream plant

16-Oct-2013 By Dan Stanton

Genzyme says it will invest $80m (€59m) in a new downstream plant to process its Fabry Disease drug, Fabrazyme.

report from Biotechnica

Better single-use cross flow techs still needed says GE Healthcare

16-Oct-2013 By Gareth Macdonald

The biopharmaceutical manufacturing sector needs better cross flow filtration technologies according to GE Healthcare, which says that advances in bioreactor systems have not been matched downstream.

Dispatches from Biotechnica

Brain AG wins award for furthering industrial biotech

16-Oct-2013 By Gareth Macdonald

Biocatalyst and microbial strain developer Brain AG was recognised for furthering industrial use of biotechnology in a ceremony at the Biotechnica trade show in Hanover, Germany yesterday.

news from Biotechnica

New Pall single-use TFF tech attracts attention

11-Oct-2013 By Gareth Macdonald

A new filter tech developed by Pall Life Sciences attracted a lot of attention at the Biotechnica trade show in Germany this week with some attendees describing it as the industry's first truly ‘single-use’ TFF module.

EMD Millipore: New chromatography offerings will meet industry need

20-Sep-2013 By Zachary Brennan

EMD Millipore on Tuesday launched a new protein A chromatography media to help biopharma manufacturers purify monoclonal antibodies, as well as new prepacked chromatography columns.

Merck Millipore says new filters ease downstream bottlenecks

18-Sep-2013 By Gareth Macdonald

Merck Millipore has launched a new range of depth filters that it claims overcome the shortcomings of traditional techs and clear a path to successful downstream clarification.

BioGenes: generic CHO HCP assays cut cost of process dev

18-Sep-2013 By Gareth Macdonald

BioGenes says a new panel of generic host cell protein (HCP) assays can help biopharmas save costs during process development.

FDA: Draft guidance on bioanalytical validation reflects tech advances

18-Sep-2013 By Zachary Brennan

The updated draft guidance calls for fully validated bioanalytical methods for any pivotal studies used to obtain approval or labelling, though less validation may be sufficient for a sponsor’s internal decision making.

Mitsubishi Closer to Buying Vax and Biosimilar Tech Developer Medicago

30-Aug-2013 By Gareth Macdonald

Mitsubishi Tanabe Pharma (MTPC) is closer to adding two plant-based expression techs to its manufacturing arsenal after Medicago shareholders back its takeover bid.

Waters Poring Over Candidates After CEO Announces Retirement Plan

28-Aug-2013 By Gareth Macdonald

Mass spec, chromatography and analytical tech firm Waters has started its search for a new CEO based on the assumption it will remain independent and keep the same growth strategy.

Small Sensors, Big BioPharma Potential Say Scientists

23-Aug-2013 By Gareth Macdonald

Large arrays of identical nanosensors could improve MAb production, identify glycosylation and pinpoint the best cell lines for biomanufacturing say US researchers.

Bio Innovators Don't Need to Be Tech "Integrators" with HarvestClear says Parker

21-Aug-2013 By Gareth Macdonald

Parker Domnick Hunter has launched a new filtration tech for antibody makers that combines know-how from several firms acquired over the past few years.

Global Bioseparation Systems Market Set to Nearly Double by 2018, Report Finds

16-Aug-2013 By Zachary Brennan

The global bioseparation systems market is projected to almost double in size from $3.25B in 2012 to $6B in 2018, at a compound annual growth rate of about 11%, according to a recent report on the market.

AB Sciex, Beckman Coulter Combine Chromatography, CE Biz as Part of Biologics Push

26-Jul-2013 By Zachary Brennan

AB Sciex is combining its chromatography business with the capillary electrophoresis (CE) business from Beckman Coulter (BC) to align BC’s expertise in microscale separation with AB’s expertise in microfluidics.

Biopharma Companies Look to New Chromatography Columns

24-Jul-2013 By Zachary Brennan

Biopharma firms, particularly those producing insulin and five of its analogues, have another option in the market of sub-2 micron solid-core chromatography columns with a recent offering from Waters.

Technology News Is Vital for BioPharmas MIT Prof Tells BioPharma-Reporter.com

16-Jul-2013 By Gareth Macdonald

Keeping up with the latest technology news is a must for biomanufacturers according to an MIT Professor who told BioPharma-Reporter.com new advances in microtechnologies could help address process development challenges.

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