Take the Right Path Upstream with MilliporeSigma | 05-Aug-2020
| Technical / White Paper
Upstream processes can be intensified using high cell density cryopreservation, perfused seed train or production processes with steady-state perfusion,...
Viral Safety for mAb: Prevent, Detect, Remove | 05-Aug-2020
| Technical / White Paper
Traditional methods for adventitious agent testing rely on biological amplification and detection, which can take several weeks. This time-consuming approach...
MilliporeSigma - Gene Therapy | 05-Aug-2020
| Technical / White Paper
While new modalities are generating significant excitement among patients and caregivers, cell and gene therapy manufacturers are experiencing growing...
Take the Right Path Upstream with MilliporeSigma | 20-Jul-2020
| Technical / White Paper
Strategies such as process intensification have the potential to create shorter lead times, reduce plant footprint, increase flexibility, and reduce COGs.
Take the Right Path Upstream with MilliporeSigma | 20-Jul-2020
| Technical / White Paper
This white paper describes process modeling and compares the process economics of a conventional upstream process versus three perfused seed train alternatives...
Take the Right Path Upstream with MilliporeSigma | 12-May-2020
| Technical / White Paper
The first commercial monoclonal antibody (mAb) was approved in 1986 and today, the global market is large and growing. Reports estimate the size of the...
Viral Safety for mAb: Prevent, Detect, Remove | 12-May-2020
| Technical / White Paper
The use of animal models for the detection of adventitious agents has been a feature of biologic testing packages for many decades. However, as alternative...
Take the Right Path Upstream with MilliporeSigma | 12-May-2020
| Technical / White Paper
The preparation of media for use in biopharmaceutical processes can be complex and may carry risks that must be identified, assessed, and mitigated to...
Eppendorf for Bioprocess – Solutions that grow with you | 10-Dec-2019
| Application Note
Experimentation at small scale is crucial for the cost-efficient development of bioprocesses, which then can be transferred to larger volumes. We have...
Eppendorf for Bioprocess – Solutions that grow with you | 01-Oct-2019
| Application Note
We successfully performed microaerobic fermenta¬tion of a probiotic strain, Lactobacillus acidophilus, at a very low oxygen level, representing the natural...
Eppendorf for Bioprocess – Solutions that grow with you | 25-Jun-2019
| Application Note
Rising interest in gene therapy-based applications leads to increasing demands in scalable production systems for viral vectors. Find out how Cevec Pharmaceuticals...
Roquette Pharma Solutions | 14-Jun-2019
| Case Study
Therapeutic proteins are inherently unstable and sensitive to temperature change, shearing, shaking, solvents, ionic strength, purity, protein concentration,...
