Low recovery for pH-sensitive antibodies and Fc-formats?
Optimize your protein A step with a novel resin for elution at higher pH levels.
Maintaining high yields can be a challenge when working with standard protein A resins, which typically elute best at pH 3 – 3.5. Praesto® Jetted A50 HipH has been designed specifically for the elution of Fc-containing molecules up to pH 5.
Developed in collaboration with Repligen Corporation, Praesto Jetted A50 HipH is the only protein A resin with this capability.
- Up to 60mg/ml dynamic binding capacity
- Elution up to pH5
- Resistant to 0.1 M NaOH for >100 CYCLES (15 min contact time)