Disposable Manufacturing Tech

BIOTECH WEEK BOSTON

MilliporeSigma claims ‘first-of-its-kind’ resin improves efficiency across the board

11-Sep-2018 By Ben Hargreaves

MilliporeSigma used Biotech Week Boston to discuss the release of its Eshmuno CP-FT resin and how it can improve downstream efficiency.

Softbox launches service to improve biopharma eco-sustainability

05-Sep-2018 By Maggie Lynch

Softbox launched its Green Recycling Service as an eco-friendly way to provide recycling options for cold-chain technology packaging components.

Q&A

Testa Center will help GE better serve bioprocessing industry, says CEO

03-Sep-2018 By Flora Southey

GE Nordics CEO Lotta Ljungqvist says the recently opened Testa Center will help facilitate innovation in the biopharmaceutical space.

ABEC to supply China’s ‘rapidly growing’ biopharma industry from Ireland

28-Aug-2018 By Flora Southey

China has accredited ABEC to make and supply bioprocessing equipment from its Kells facility in Ireland.

GE Healthcare opens bioprocessing ‘test bed’ for biotechs

21-Aug-2018 By Flora Southey

The Testa BioProcess Innovation Center in Sweden will help academics, startups, and biopharmaceutical companies secure industrial proof-of-concepts quicker, and with less cost, says GE Healthcare.

Amgen begins work on $200m ‘next-gen’ biomanufacturing site

10-Aug-2018 By Ben Hargreaves

Amgen has broken ground on the construction of its West Greenwich, Rhode Island-based 120,000-square-foot biomanufacturing facility.

Entegris: Growing demand for single-use tech drives Flex Concepts buy

03-Jul-2018 By Flora Southey

Entegris says buying Flex Concepts will help secure its supply of disposable bioprocessing bags and fluid transfer technologies.

Parker details investment timeline, launches new single-use system

12-Jun-2018 By Melissa Fassbender

Parker Bioscience outlines its planned investment to meet demand as the industry shifts from traditional processes to biological – for which single-use products are critical, says exec.

UK invests in cell and gene therapy workforce to prepare for commercial products

29-May-2018 By Nick Taylor

The UK is investing £3m ($4m) to build a workforce capable of delivering cell and gene therapies to patients at commercial scales.

INTERPHEX 2018

Avid Bioservices: 'The single-use facility is not all sunshine'

18-May-2018 By Flora Southey

Fluid distribution and warehouse management challenges are among the ‘pitfalls’ of the single-use biopharmaceutical facility, says Avid Bioservices executive.

INTERPHEX 2018

MilliporeSigma looks beyond ‘burn and bury’ for single-use recycling

24-Apr-2018 By Flora Southey

MilliporeSigma is urging industry to recycle single-use technologies, which can be made into speed pumps, parking bollards, and plastic palettes.

INTERPHEX 2018

MilliporeSigma ups single-use mixer volume to 3,000L

20-Apr-2018 By Flora Southey

MilliporeSigma has launched a new Mobius Power MIX single-use mixing system for buffers, cell culture media powders, and ingredients.

Pall and Artesyn Biosolutions team to industrialize single-use tech

18-Apr-2018 By Melissa Fassbender

Pall Corporation and Artesyn Biosolutions will co-develop clinical to commercial-scale solutions for single-use automated bioprocessing systems.

GE launches modular bioprocessing facility for viral vector vaccines

17-Apr-2018 By Flora Southey

GE Healthcare Life Sciences has launched a prefabricated, modular bioprocessing facility designed for the manufacture of viral vector-based therapeutics.

Bio-Separation: Our outgoing editor looks back over 5 years

13-Apr-2018 By Dan Stanton

Biopharma-Reporter editor Dan Stanton is finally packing his buffer bag and moving upstream.

Sanofi: €350m vaccine investment part of ‘digital factory’ ambition

13-Apr-2018 By Dan Stanton

A new vaccine manufacturing facility in Toronto, Canada will boast single-use tech and closed continuous process to help improve productivity and performance, Sanofi says.

UPDATE

Amgen picks Rhode Island location for next-gen biomanufacturing

11-Apr-2018 By Flora Southey

Rhode Island will be the home of Amgen’s first US next-generation biomanufacturing plant, based on the firm’s modular, single-use site in Singapore.

MilliporeSigma: Filling gaps in continuous bioprocessing will lower COGS

10-Apr-2018 By Dan Stanton

Vendors can help address technology gaps but industry must look to collaborations and internal development to create fully continuous bioprocesses, says MilliporeSigma.

Bioprocessing overlap: Taking lessons from small molecule makers

03-Apr-2018 By Dan Stanton

Process control, quality management and training operators are areas where biomanufacturers can learn from small molecule makers, according to preliminary results from a BioPlan Associates survey.

Back to school: Shire trains at NIBRT ahead of biologics site opening

28-Mar-2018 By Flora Southey

Shire is sending its employees to the National Institute for Bioprocessing and Research Training prior to opening its biomanufacturing site in Dunboyne, Ireland.

Takeda’s off-the-shelf stem cell therapy approved in Europe

27-Mar-2018 By Dan Stanton

Alofisel (darvadstrocel) has become the first allogeneic stem cell product to be approved in Europe.

WuXi Biologics adds 4,000L bioreactors at fully single-use site

21-Mar-2018 By Dan Stanton

The CMO says adding the single-use offering from ABEC will make the newly opened biomanufacturing site in China comparable to stainless steel for commercial mAb production.

News in brief

ABL Europe equips viral vector plant with Sartorius single-use tech

16-Mar-2018 By Staff Reporter

Both upstream and downstream systems provided by Sartorius Stedim Biotech have been installed in ABL’s facility in Strasbourg, France.

Fujifilm to make AAVs for Regenxbio gene therapies

13-Mar-2018 By Staff Reporter

Regenxbio says a manufacturing contract with Fujifilm Diosynth Biotechnologies will support its gene therapy candidates.

AGC Biologics adds 2,000L single-use bioreactor in CA

09-Mar-2018 By Dan Stanton

The biologics CDMO will install a 2,000L single-use bioreactor (SUB) from Thermo Fisher Scientific at its Berkeley facility to meet demand for early-phase projects.

Beyond mammalian culture: ABEC’s single-use range to cover microbial fermentation

07-Mar-2018 By Flora Southey

Bioprocessing vendor ABEC has added microbial fermentation capabilities to its single-use line.

Draper touts new bioprocessing method as ‘next big advance in CAR T-cell treatment’

02-Mar-2018 By Melissa Fassbender

Draper has designed a microfluidic transduction device (MTD) it claims will help CAR T-cell therapy developers lower costs, up efficiency – and potentially bring manufacturing to the patient’s bedside.

Perfusion to fed-batch: Repligen record quarter for ATF tech

23-Feb-2018 By Dan Stanton

Repligen says the single-use version of its alternating tangential flow (ATF) platform is helping the firm capture a larger share of the fed-batch bioreactor marketplace.

Amgen: Tax reforms stoke $300m investment in next-gen US biomanufacturing plant

02-Feb-2018 By Dan Stanton

Amgen has announced plans for a US biomanufacturing facility, similar to its flexible and single-use Singapore plant, as part of $3.5bn freed through tax reforms.

Pall the ‘stand-out’ in Danaher’s life sciences Q4 results

31-Jan-2018 By Staff Reporter

Pall Corporation reported its best quarterly growth since its acquisition by Danaher in 2015.

Bigger in Texas: Fujifilm adds 6,000L and opens gene therapy plant

30-Jan-2018 By Dan Stanton

The need for CDMOs with commercial gene therapy capacity is growing says Fujilfilm Diosynth Biotechnologies, which has opened an 80,000 square-foot plant in Texas.

GE wins another FlexFactory fit out in ‘big market’ China

24-Jan-2018 By Flora Southey

Clover Biopharmaceuticals will adopt GE Healthcare’s centrally automated FlexFactory platform at its facility in Zhejiang, China where it plans to make a biosimilar to Amgen’s Enbrel.

Paragon expansion to address ‘deficit in gene therapy CDMO capacity’

24-Jan-2018 By Dan Stanton

The CDMO says it is building a 150,000 square-foot biomanufacturing facility in Maryland in preparation for a double-digit growth in the gene therapy space.

Sanofi to pay $11.6bn for Bioverativ for haemophilia biz and commercial network

23-Jan-2018 By Gareth Macdonald

Sanofi has agreed to buy Bioverativ Inc. for $11.6bn for haemophilia business and to help develop its candidate RNAi therapeutic fitusiran.

Cellular Biomedicine Group adopts GE Healthcare tech for CAR-T therapy production

19-Jan-2018 By Gareth Macdonald

Cellular Biomedicine Group Inc (CBMG) has selected GE Healthcare’s FlexFactory technology for its CAR-T therapy production facility in Shanghai, China.

Meissner expands aseptic fill/finish range through PDC acquisition

18-Jan-2018 By Staff Reporter

Meissner Filtration Products has bolstered its automated filling offerings through the acquisition of PDC Aseptic Filling Systems.

Abzena selects Sartorius single-use bioreactors for US sites

05-Jan-2018 By Flora Southey

Sartorius Stedim Biotech will supply disposable bioreactors at Abzena’s CDMO facilities in the US.

Abzena ups and integrates biomanufacturing and conjugation capabilities

12-Dec-2017 By Dan Stanton

Abzena has negotiated the lease on a 50,000 square foot site in San Diego as part of a $17m remodelling of its bioproduction and conjugation facilities.

Standardised single-use tech, the industry’s 'holy grail?'

06-Dec-2017 By Flora Southey

Vendors say they are open to considering a singular, industry-wide design for disposable bioreactor equipment, IP concerns and customised demands could impede its adoption.

World’s largest single-use plant begins cGMP production

06-Dec-2017 By Dan Stanton

WuXi Biologics says its 30,000L capacity single-use facility in China has commenced making products for its partner Tesaro.

News in Brief

Stax to the mAx? Pall launches single-use mAb harvesting tech

22-Nov-2017 By Staff Reporter

Pall Corporation has launched a monoclonal antibody clarification platform without centrifugation or process additives to support cell cultures of up to 2,000L.

Additive value: Inside GE Healthcare’s 3D printing and design lab

21-Nov-2017 By Dan Stanton

GE Healthcare opened its European Innovative Design and Advanced Manufacturing Technology Center last month. Biopharma-Reporter took a visit to Uppsala, Sweden to find out more.

ABEC: customised tech protects large single-use bags

17-Nov-2017 By Flora Southey

A pulley loading system and customised storage frame reduces damage risk to large single-use bags, says 4,000L bioreactor vendor ABEC.

Avid letting Peregrine fly off as it focuses on bio-CDMO business

16-Nov-2017 By Dan Stanton

Peregrine Pharmaceuticals will become a pure-play CDMO under the name Avid Bioservices and is looking to sell or license its pipeline, including investigational monoclonal antibody bavituximab.

Merck KGaA: Extensive uptake of single-use forced efficiency drive

10-Nov-2017 By Dan Stanton

Single-use demand grew so fast vendors were unable to keep up, says MilliporeSigma which has since tackled this through investments and a standardised offering.

Samsung BioLogics extends supply agreement with MilliporeSigma

08-Nov-2017 By Dan Stanton

Samsung BioLogics has extended a memorandum of understanding with MilliporeSigma for supply of single-use systems and bioprocessing raw materials.

Catalent: Cook deal strengthens sub 5,000L scale CMO strategy

08-Nov-2017 By Dan Stanton

70% of the biologics pipeline will require less than 5,000L of commercial manufacturing capacity says Catalent, fresh from its acquisition of Cook.

Swiss CDMO to expand newly bought Glycotope biomanufacturing plant in Germany

07-Nov-2017 By Dan Stanton

Celonic says it will immediately begin expanding the former Glycotope site in Heidelberg, Germany adding two 2,000L single-use bioreactors.

Fujifilm adding three 2,000L GE single-use bioreactors as part of $30m expansion

06-Nov-2017 By Dan Stanton

Following a ‎¥14bn ($125m) investment in April, Fujifilm Corporation has committed a further ‎¥3.2bn across its biologics contract manufacturing business.

Pall lands WuXi fit out for mAb continuous bioprocess lab

03-Nov-2017 By Flora Southey

Pall Corporation will equip WuXi Biologics’ continuous bioprocess laboratory in Shanghai, China, which the latter said would expand process scale and reduce manufacturing costs.