UPDATE

Amgen picks Rhode Island location for next-gen biomanufacturing

By Flora Southey contact

- Last updated on GMT

GettyImages/Posnov
GettyImages/Posnov
Rhode Island will be the home of Amgen’s first US next-generation biomanufacturing plant, based on the firm’s modular, single-use site in Singapore.

The facility will be located on the same 75-acre campus as Amgen’s manufacturing site in West Greenwich, where the firm makes clinical bulk drug substances.

Two months ago, Amgen announced plans​ to build a facility at an estimated cost of $300m, but a spokesperson told us today the cost has reduced to approximately $165m “because it will be built at an existing Amgen site.”

The project is part of a larger plan to invest around $3.5bn (€2.8m) in capital expenditures in the US over the next five years, as a result of the last year’s tax reform.

As of December 2017, the US corporate tax rate​ has dropped from 35% to 21%, which provides incentive for firms to invest in the country and repatriate cash held overseas.

Site construction will be completed in 2020, and add approximately 150 manufacturing jobs and 200 construction and validation positions.

Next-generation?

According to Amgen, a ‘next-generation’ biomanufacturing facility can be built in half the construction time of a traditional plant, and requires half the operating costs.

The concept involves a smaller manufacturing footprint and can help lower water and energy consumption, as well as reduce carbon emissions.

Amgen’s $200m next-generation biomanufacturing plant opened in Singapore in 2014​. The site houses single-use bioreactors, continuous purification processing, and real-time quality analysis technology.

Keeping in line with the next-gen formula, the site was completed in half the time required for a traditional plant, and Amgen said its modular design enables the firm to eliminate costly and complex retrofitting when structuring changes.

Related news

Show more

Related products

show more

Removing Aggregates of an Acidic Monoclonal Antibody

Removing Aggregates of an Acidic Monoclonal Antibody

Bio-Rad Laboratories | 22-Oct-2018 | Technical / White Paper

CHT Ceramic Hydroxyapatite Media/Resins are known as the industry gold standard for
impurity removal during monoclonal antibody (mAb) purification....

Single-Step Influenza and Dengue Virus Purification

Single-Step Influenza and Dengue Virus Purification

Bio-Rad Laboratories | 08-Oct-2018 | Application Note

CHT XT is the newest addition to the CHT family of media. It has been designed for superior physical robustness to ensure it can be used repeatedly over...

Downstream Purification of Large Biomolecules

Downstream Purification of Large Biomolecules

Bio-Rad Laboratories | 17-Sep-2018 | Research Study

Our newest strong anion exchange resin provides both high binding capacity and
high recovery, even at high flow rates. A rigid bead complete with...

Cultivation of 3D Cell Aggregates in Perfusion

Cultivation of 3D Cell Aggregates in Perfusion

Eppendorf for Bioprocess – Solutions that grow with you | 17-Sep-2018 | Application Note

3D cell aggregates are of great interest for applications like disease modeling and manufacturing of stem cell-based products. Read more about the cultivation...

Related suppliers

Follow us

Products

View more

Webinars