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Scale-Up of Multicolumn Chromatography

Format: PDF file | Document type: Application Note

The Cadence™ BioSMB platform from Pall Life Sciences is the first disposable flow path, continuous multicolumn chromatography solution that is fully scalable from the process development (PD) laboratory to cGMP manufacturing.

The Cadence BioSMB Process System is specifically designed to allow users to convert an existing PD scale continuous purification into a process scale continuous purification based on feedstreams derived from fed batch bioreactors of up to 2000 L.

Download an application note to learn how Merck made the transition from PD to commercial manufacture within 4 weeks.