Upstream Processing

iBio activates sterile fill-finish operations for clinical stage biopharma

27-Jun-2019 By Maggie Lynch

Sterile fill-finish capabilities will be available to clinical stage customers as iBio activates its operations for biopharmaceutical products after entering a supply agreement.

Sartorius’ $100m Puerto Rico expansion enables greater supply for US industry

26-Jun-2019 By Maggie Lynch

Sartorius’ investment in Puerto Rico site doubles production capacity of manufacturing equipment for the biopharmaceutical industry.

Merck to use prefabricated adjustable cleanrooms at $300m FLEx center

18-Jun-2019 By Maggie Lynch

Reconfigurable cleanroom pods to be used at Merck’s formulation laboratory to address increasing demands of diverse patient populations.

Bluebird chooses partner for manufacture of its first approved product

13-Jun-2019 By Ben Hargreaves

Apceth announces that it will be responsible for the commercial manufacture of Zyntelgo, after its approval last week.

Single-use tech ‘reshaping’ the industry as Thermo Fisher further invests

11-Jun-2019 By Maggie Lynch

Thermo Fisher invests into bioproduction capabilities as ‘single use continues to reshape the face of the industry,’ says single-use technology executive.

Lonza adopts Synpromics’ inducible promoters, expands bio manufacturing platform

22-May-2019 By Vassia Barba

Lonza and Synpromics move on to the commercialization of a number of inducible promoters to expand the former’s manufacturing offerings.

Bayer invests $150m to expand its biologics development

14-May-2019 By Ben Hargreaves

Bayer will build a 40,000-square-foot cell culture facility to bolster its capacity to develop therapies primarily focused on oncology and cardiology.

Fujifilm Irvine Scientific launches insect cell media for viral vectors

29-Mar-2019 By Ben Hargreaves

Fujifilm Irvine Scientific announces low hydrolysate medium for use in insect cell expression systems.

MaSTherCell brings ‘large-scale’ advanced therapeutics manufacturing to Europe

28-Mar-2019 By Ben Hargreaves

The CDMO leases a facility in Belgium to manufacture cell and gene therapies at a large-scale, in a move the company claims is a first in Europe.

Pall agrees to develop New Jersey cell and gene therapy sites

26-Mar-2019 By Ben Hargreaves

Pall Biotech signs an industry participation agreement with the New Jersey Innovation Institute to create two centres designed to develop and manufacture cell and gene therapies.

Cellectis to build CAR-T manufacturing sites in US and Europe

14-Mar-2019 By Ben Hargreaves

In a step towards the commercialisation of its ‘off-the-shelf’ CAR-T therapies, Cellectis begins construction of a facility in France and enters lease agreement for US facility.

Fujifilm continues ‘aggressive’ expansion with $890m site purchase

12-Mar-2019 By Ben Hargreaves

Fujifilm continues investment in its manufacturing capabilities through the acquisition of a large-scale biologics site from Biogen.

Kite collaborates to increase efficiency of CAR-T manufacture

07-Mar-2019 By Ben Hargreaves

MaxCyte announces a partnership with Kite to explore the use of flow electroporation technology to enable the non-viral cell engineering of CAR-T drug candidates.

Krystal moves towards ‘full integration’ with gene therapy facility opening

07-Mar-2019 By Ben Hargreaves

Krystal opens cGMP facility for the clinical and commercial manufacture of its lead drug candidate, KB103, and plans to open its second in 2020.

GE Healthcare working ‘two to three years’ ahead anticipating manufacturing advances

06-Mar-2019 By Ben Hargreaves

The rapid evolution of cell and gene therapy technology is leading GE Healthcare to explore partnerships to meet increasing manufacturing demand, according to the company's enterprise solutions leader.