Ajinomoto to produce potential COVID-19 treatment for CytoDyn

By Ben Hargreaves contact

- Last updated on GMT

(Image: Getty/Duncan Andison)
(Image: Getty/Duncan Andison)

Related tags: Ajinomoto Bio-Pharma, CytoDyn, COVID-19, Coronavirus, Leronlimab

Ajinomoto agrees partnership to manufacture leronlimab, which is currently undergoing clinical trials for the treatment of COVID-19.

CytoDyn’s potential treatment, leronlimab, is currently being tested for patients deemed ‘mild-to-moderately ill’ and ‘severely ill’ with COVID-19.

According to the company, the treatment is being administered to patients in the New York City area as part of Phase I, Phase III, and Phase IIb/III clinical trials.

In order to ensure supply, CytoDyn has signed an extended manufacturing agreement with Ajinomoto Bio-Pharma Services for aseptic fill-finish services.

The two partners had already been working together for production of leronlimab for other therapeutics indications.

CytoDyn is exploring the monoclonal antibody for use across a variety of indications, including against HIV as both a monotherapy and as part of a combination treatment, which are both at the Phase III stage.

The company has also taken the treatment to Phase II stage for triple-negative breast cancer and Phase II against a total of 22 solid tumor types.

Leronlimab blocks the CCR5 cellular receptor, which is thought to play a role in tumor metastases and is an indicator of disease status in some cancers. It also plays a role in inflammatory conditions by modulating immune cell trafficking to areas of inflammation, the company suggested.

Yesterday, CytoDyn announced that it had submitted a request to the US Food and Drug Administration for ‘compassionate use’ of patients currently ineligible for its two ongoing clinical trials for COVID-19 patients. Currently, the company has 49 patients enrolled for treatment.

Related news

Show more

Related products

show more

dPCR Case Study

dPCR Case Study

CellCarta | 08-Aug-2022 | Case Study

Streamline your adoptive cell therapy program with digital PCR. Our team has a unique expertise in digital and quantitative PCR to support you in ensuring...

The Reagents Behind Much of Molecular Biology

The Reagents Behind Much of Molecular Biology

Thermo Fisher Scientific | 25-Jul-2022 | Case Study

The ability to amplify, modify and fabricate DNA is fundamental to modern molecular biology. Why do so many researchers take their constituent parts for...

Fill-Finish Biologics

Fill-Finish Biologics

Curia | 16-May-2022 | Technical / White Paper

The clinical value of biologics for the treatment of many disease indications has been accompanied by phenomenal sales. By 2026, the global market for...

Microsampling in Early Phase Drug Development

Microsampling in Early Phase Drug Development

Altasciences | 10-May-2022 | Technical / White Paper

Microsampling significantly lessens the volume of blood and plasma/serum that is collected and analyzed to determine circulating concentrations of therapeutic...

Related suppliers

Follow us

Products

View more

Webinars