Bioreactors

Provenge CMO PharmaCell contracted for 2nd product

24-Jan-2014 By Gareth Macdonald

PharmaCell, the CMO that makes Provenge for Dendreon in Europe, has agreed to buy a facility from TiGenix to add capacity and a manufacturing contract for a second commercial product.

Nanotherapeutics opts for GE’s modular manufacturing platform

22-Jan-2014

US defence contractor Nanotherapeutics will use a modular biomanufacturing system provided by GE Healthcare at a facility it is building in Alachua, Florida.

Man-made tracheas move into clinical trial manufacturing phase

22-Jan-2014 By Zachary Brennan

Synthetically engineered tracheas may be marketed sooner than previously thought as a Harvard Bioscience spinoff prepares to produce the “scaffolds” for growing tracheas in more clinical trials.

Pall CEO: ATMI deal doesn't rule out other acquisitions

21-Jan-2014 By Dan Stanton

Buying ATMI will help Pall fill gaps in its up and downstream biomanufacturing tech offerings but the deal does not rule out other acquisitions says CEO, Larry Kingsley

China OKs $13bn Life Tech takeover but insists on Thermo price cuts

15-Jan-2014 By Gareth Macdonald

Chinese authorities have given Thermo Fisher Scientific the green light to buy Life Technologies on the condition it discounts certain products sold in the coutry.

UPDATE

ATMI sells bioreactor biz to Pall following strategic review

23-Dec-2013 By Dan Stanton

Pall Corporation has acquired ATMI’s Life Science Business for $185m (€135m).

Sartorius sets out plans for Ambr after Tap takeover

20-Dec-2013 By Gareth Macdonald

Sartorius has confirmed it will make the Ambr microreactor technology it acquired with Tap Biosystems compatible with its own downstream processing systems.

Cellexus claims new bioreactor better at mixing than rocking systems

06-Dec-2013

Cellexus has launched a new bioreactor system that employs an air-based mixing system that is better at aerating cell cultures than rocking or large chamber systems.

Cobra says the right tech strategy can cut lead times

02-Dec-2013 By Gareth Macdonald

Choosing the same biomanufacturing tech supplier for development and commercial systems cuts scale steps and reduces lead times according to Cobra Biologics.

TAP approves Sartorius $45m takeover bid

22-Nov-2013

UK-based fermentor maker TAP Biosystems has approved the €33m ($45m) takeover bid by Sartorius.

GE launches new programmable bioreactor for seed chain and process dev

22-Nov-2013 By Gareth Macdonald

GE Healthcare has launched new single-use, bioreactor for seed train and process development operations and mAb production.

GE expands cell expansion offering targeting cell therapy firms

15-Nov-2013 By Gareth Macdonald

GE Healthcare has launched a cell expansion technology designed to win business from cell therapy developers.

Orgenesis and ATMI partner in diabetes cell therapy Belgian subsidiary

08-Nov-2013 By Dan Stanton

Orgenesis has partnered ATMI and established a subsidiary in Belgium in order to manufacture cells for clinical trials of its insulin-producing regenerative drug.

Applikon says new HQ will help meet biopharma demand

06-Nov-2013 By Gareth Macdonald

Bioreactor manufacturer Applikon Biotechnology has officially opened its new headquartered and manufacturing centre this week.

ATMI begins strategic review but says bioreactors business is on track

06-Nov-2013 By Gareth Macdonald

ATMI has started exploring strategic alternatives but insists that its bioreactor business is positioned to benefit from increasing biopharma demand for single-use techs.

update

Lack of US FDA biosimilars guidance not holding back global dev say EMA meeting attendees

31-Oct-2013 By Gareth Macdonald

The lack of US FDA biosimilars guidance is not holding back development say BioPharmas and regulators who met with the EMA this week.

Cobra Biologics moves to beef up mAb capacity

30-Oct-2013 By Gareth Macdonald

Corba Biologics has opted for a HyClone bioreactor to boost its antibody production capacity citing customer demand and biosimilars as the drivers for the investment.

Pall opens Centre of Excellence in Shanghai

25-Oct-2013 By Dan Stanton

Pall has opened of a Centre of Excellence (CofE) in Shanghai for both local and international customers.

Nanotherapeutics to invest $122m to make biologics for US military

25-Oct-2013

Biologics firm Nanotherapeutics has started work on a new facility that will produce biological countermeasures for the US military.

EDITOR'S BLOG

Plastic not fantastic but single-use is still greener, says industry

04-Oct-2013 By Dan Stanton

Plastic may be greener than stainless steel, but industry still needs to find a more recyclable alternative for biomanufacturing systems according to Greenpeace.

Gallus doubles biologics capacity with acquisition of CMO Laureate

02-Oct-2013 By Dan Stanton

Gallus Biopharmaceuticals has doubled its biologics process development services with the acquisition of contract manufacturer Laureate.

Fujifilm Diosynth Biotechnologies opts for Xcellerex tech at new UK plant

02-Oct-2013 By Gareth Macdonald

Fujifilm Diosynth Biotechnologies has opened a mammalian cell culture-based manufacturing facility in the UK in the latest stage of an effort to expand its business.

GE to build disposable biopharmaceutical factory for JHL Biotech in China

27-Sep-2013 By Zachary Brennan

GE Healthcare Life Sciences has agreed to build a modular biopharmaceutical factory in China for JHL Biotech, which could be a model for ways to grow local manufacturing in emerging markets. 

MIT’s biomanufacturing program wins $10M US defense contract

20-Sep-2013 By Zachary Brennan

The US Defense Advanced Research Projects Agency (DARPA) has awarded MIT’s Biomanufacturing Research Program (BioMAN) a $10.4 million grant from to develop devices and techniques to more rapidly produce biologics. 

Eppendorf Gets US Patent for ‘Unopenable’ Bioreactor

13-Sep-2013 By Gareth Macdonald

Eppendorf claims its new bioreactor design overcomes the contamination risk associated with more easily opened systems.

EDITOR'S BLOG

BioPharma Tech Firms Can Help Prevent Bioweapon Production, Says UN

11-Sep-2013 By Gareth Macdonald

Making germ warfare weapons is banned under the Biological Weapons Convention (BWC) and there is no evidence signatories or even countries led by any of the World’s crackpot dictators/freedom fighters* are producing them.

Report: Biopharma Industry’s Growth Driven By mAb Development

11-Sep-2013 By Zachary Brennan

The $165bn biopharma market is expected to grow by about 15% annually, driven largely by increasing revenue growth from recombinant monoclonal antibodies (mAbs), according to a recent report.

Single-Use Growth Offsets Pall's Muted Results

30-Aug-2013 By Dan Stanton

Pall Corporation says it will continue to invest in single-use systems after reporting substantially higher growth in sales compared to stainless steel systems for the 2013 FY.

Questions of Value Raised over Amgen Purchase of Onyx as Stock Slips

28-Aug-2013 By Zachary Brennan

Investors on Tuesday seemed a little less sure of biopharma behemoth Amgen’s decision to purchase cancer specialist Onyx for more than $10B over the weekend. 

Agilent Looks to Expand Access to Biomarker Discovery Platform

16-Aug-2013 By Zachary Brennan

Agilent Technologies is partnering with SomaLogic to expand the dissemination of Soma’s proteomic assay to at least five academic and contract research centers by the end of the year as demand for the tool has skyrocketed among biopharma companies.

Regeneron to Add 2 New Bioreactors in NY Plant Expansion

14-Aug-2013

Regeneron will add two new 10,000-litre bioreactors at its East Greenbush facility as part of an $80m expansion.

Uptake in Single-Use is Changing Facility Design, Experts Say

14-Aug-2013 By Dan Stanton

Adapting stainless steel facilities to incorporate increased use of disposable technology can help reduce costs and improve quality compliance, say TFS and Lonza.

Lonza Licenses Expression Tech to Second Firm in Two Weeks

07-Aug-2013 By Gareth Macdonald

Lonza has granted access to its potency boosting expression system to antibody developer Sorrento Therapeutics just days after a signing a similar deal with Pfizer.

Thermo Fisher Opens First Dry Powder Media Plant in Singapore

07-Aug-2013 By Dan Stanton

Growing demand amongst biomanufacturers has prompted Thermo Fisher to open the first dry powder media (DPM) production plant in Singapore.

Sartorius and BlueSens Partner on Microbial Gas Sensor Tech

24-Jul-2013 By Dan Stanton

Industry has been slow to implement single-use technologies for microbial cultivations, according to Sartorius which has launched a new bioreactor gas sensor.

Uptake of Single-Use Bioreactors Expected to See Massive Growth, Experts Say

17-Jul-2013 By Zachary Brennan

As biopharma manufacturers look to save money setting up facilities and cleaning equipment, companies are increasingly turning to single-use technology and especially single-use bioreactors.

Technology News Is Vital for BioPharmas MIT Prof Tells BioPharma-Reporter.com

16-Jul-2013 By Gareth Macdonald

Keeping up with the latest technology news is a must for biomanufacturers according to an MIT Professor who told BioPharma-Reporter.com new advances in microtechnologies could help address process development challenges. 

Correction

Pfizer Preps for Pipeline with $130m Irish Investment

11-Jul-2013 By Dan Stanton

After patent expiration led to facility shuttering and cutbacks, Irish manufacturing will receive a $130m (€100m) boost to prepare for Pfizer’s new pipeline, the company says.

Brazil's $280m Deal to Manufacture and Market Gaucher's Disease Drug

20-Jun-2013 By Dan Stanton

The Brazilian Government is to fund a new facility to produce the Protalix-Pfizer Gaucher's disease drug Uplyso as part of a supply and tech transfer deal worth $280m (€212m).

Update

Thermo Fisher Acquires Life Tech for $13.6B

15-Apr-2013 By Zachary Brennan

Thermo Fisher Scientific has agreed to purchase genetic testing equipment maker Life Technologies for $13.6B in one of the biggest acquisitions of the year.

BMS Plant Expansion to Push Biologics Development and Manufacturing

15-Apr-2013 By Dan Stanton

Bristol Myers-Squibb says its $250m (€191m) expansion of its US biologics facility will centralize its processes and become a springboard to launch new products.

ATMI: Single Use Bioreactors on the Up, but US Tails Europe

20-Feb-2013 By Dan Stanton

New innovations in single-use bioprocessing systems are being picked up quicker in Europe than in the US, according to ATMI.

Update

Baxter Expands its Cytotoxicity Capabilities - Again

19-Feb-2013 By Dan Stanton

Baxter says there is a trend towards outsourcing for cytotoxic manufacturing as it begins further expansion of its German plant.

Catalent plans single use overhaul of bioreactors

31-Jul-2012 By Natalie Morrison

Catalent has replaced all stainless steel bioreactors at its biologics facility in Middleton, Wisconsin with single-use techs citing cost and flexibility advantages.

ATMI acquires Artelis in ‘disposables’ deal

04-Nov-2010 By Alexandria Pešić

ATMI has acquired Artelis, a Belgian biotech firm, in an effort to “get closer to customers” by widening its disposable technology portfolio to the life sciences research and manufacturing sector.

Celleuxs launches “broad cell line” disposable bioreactor

28-Jul-2010 By Gareth Macdonald

Cellexus has expanded its disposable bioreactor offering with a unit designed to give biomanufacturers greater flexibility in their choice of cell lines.

ATMI introduces disposable bioreactor

22-Apr-2010 By Nick Taylor

ATMI is using Interphex 2010 to launch the Integrity PadReactor, a disposable bioreactor designed to provide a highly scalable entry point in its line of mixing and process manufacturing systems.