Experimentation at small scale is crucial for the cost-efficient development of bioprocesses, which then can be transferred to larger volumes. We have...
We successfully performed microaerobic fermenta¬tion of a probiotic strain, Lactobacillus acidophilus, at a very low oxygen level, representing the natural...
Rising interest in gene therapy-based applications leads to increasing demands in scalable production systems for viral vectors. Find out how Cevec Pharmaceuticals...
Roquette Pharma Solutions | 14-Jun-2019
| Case Study
Therapeutic proteins are inherently unstable and sensitive to temperature change, shearing, shaking, solvents, ionic strength, purity, protein concentration,...
CHT XT is the newest addition to the CHT family of media. It has been designed for superior physical robustness to ensure it can be used repeatedly over...
3D cell aggregates are of great interest for applications like disease modeling and manufacturing of stem cell-based products. Read more about the cultivation...
A desperate mother in Germany urged her team of doctors to reach out to a Marken client on behalf of her two year old girl. The child was battling leukemia...
Would you like to enhance your downstream process, increase production capacity and reduce costs? This case study application note demonstrates how implementing...
Viral diseases like rabies, rotavirus and influenza are causing many deaths worldwide, resulting in a strong demand for more productive manufacturing techniques...
Aflibercept (Zaltrap®) is a recombinant fusion protein with complex post-translational modifications. Therefore deep understanding of biosimilar development...
Download the eBook written by Catalent experts to learn about innovative products and techniques for scale-up of complex biologics, get optimal cell culture...
The Cadence inline diafiltration (ILDF) device is designed for continuous processing, in-process buffer exchange or contaminant removal in various processes...
At Pall we have supported the water intrusion test for more than 20 years and we developed the Palltronic® AquaWIT IV system to deliver fast and simple...
Pall’s Supor ® buffer filters are designed for high flow rates and rapid microbial removal. This can mean dramatic reductions in buffer handling costs...
In September 2017, BioPharma-Reporter.com conducted its second annual ‘state of the industry’ survey on its user base of biopharmaceutical industry professionals....
Watch our video above to learn more about the history of Purolite Life Sciences.To discuss how we can assist your journey to process excellence, please...
The Mastercycler X50 is Eppendorf's new PCR cycler with lots of new benefits. Not only can you heat with 10°C/s, you can also optimize two different...
DNA concentration, mastermix preparation, temperature management: Doing PCR like a pro can be more complex than it seems.The Eppendorf infographic helps...
The Cadence™ BioSMB platform from Pall Life Sciences is the first disposable flow path, continuous multicolumn chromatography solution that is fully scalable...
mAbs are produced for a number of therapeutic applications. However, mAbs are not a homogeneous family of products. Each mAb is unique, based on its isoelectric...
Pall Biotech | 01-Jun-2017
| Technical / White Paper
For many years cylindrical stainless steel tanks have been used in biopharmaceutical production.The primary reason for the cylindrical shape was that it...
Continuous manufacturing has been established in several processing industries for many years, providing many benefits over batch manufacturing. Until...
Single-use bioreactors have only been cylindrical in design, until now. The Allegro™ STR single-use, stirred tank bioreactor provides advantages over the...
The Auto Culture modes, standard on the Eppendorf BioFlo® 120 bioprocess control station, offer push-button automatic process control for some of the most...
With the rising interest in biopharmaceuticals, drug developers need to quickly understand and evaluate the binding of therapeutic antibodies to Fc receptors. ...
Baxter BioPharma Solutions | 13-Feb-2017
| Technical / White Paper
The ultimate goal of formulation development is a stable product. In the case of a protein product, that can be defined as delivering the correct dose,...
With the increasing complexity of biologics and growing competition with players ranging from small start-ups to large pharma, an aggressive development...
Applikon Biotechnology | 24-Oct-2016
| Technical / White Paper
Biological product engineering relies on selecting the best performing microbial strain and finding optimal culture conditions. The screening for these...
Virus filtration is a vital part of the viral clearance strategy in bioprocesses. In filtration, size exclusion mechanisms are orthogonal to other inactivation...
Applikon Biotechnology | 19-Sep-2016
| Research Study
The micro-Matrix allows rapid screening of large number of organisms and optimize media conditions. Individual and continuous measurement and control of...
Regulatory authorities require head-to-head comparison at multiple levels to demonstrate that a proposed biosimilar is “similar or highly similar” to the...
World Courier | 12-Sep-2016
| Technical / White Paper
Take your clinical trials to the next level. The direct-to-patient (DtP) model solves two of the largest issues plaguing clinical trials: patient recruitment...
Pall Biotech | 25-Jul-2016
| Technical / White Paper
Learn the advantages of transferring from single column to continuous chromatography processes with connected unit operations. This poster titled “Demonstration...
Therapeutic proteins such as monoclonal antibodies and fusion proteins represent one of the fastest growing segments in the drug pipeline, which puts pressure...
In May 2016, BioPharma-Reporter conducted its inaugural ‘state of the industry’ survey. The key objective of the poll was to gauge views about the current...
The iLine F microscope changes the way you count your suspension cells. It continuously and automatically analyzes images of your cells, discriminates...
SGS Life Science Services | 16-May-2016
| Technical / White Paper
The detection of mycoplasma contamination is of utmost concern in bio-therapeutic and vaccine manufacturing. The two pharmacopeia techniques rely on the...
Pall Biotech | 18-Apr-2016
| Technical / White Paper
Learn how single-pass tangential flow filtration (SPTFF) technology is revolutionizing current and future bioprocessing platforms with its implementations...
World Courier | 29-Mar-2016
| Technical / White Paper
Orphan drugs, those medications that are typically produced in small quantities for limited patient populations, are growing in importance worldwide. Once...
SGS Life Science Services | 21-Mar-2016
| Technical / White Paper
Using case studies, this white paper demonstrates the advantages and versatility of LC-MS/MS in analyzing biomolecular drugs and biomarkers at all stages...
The global pharmaceutical industry will have spent more than $10 billion on cold chain logistics in 2015, getting products and clinical trial supplies...
Applikon Biotechnology | 29-Feb-2016
| Technical / White Paper
Apart from partial or total joint replacement, no surgical procedure is currently available to treat large and deep cartilage defects associated with advanced...
World Courier | 22-Feb-2016
| Technical / White Paper
In the world of clinical trials, one of the greatest challenges to overcome is the recruitment and retention of qualified patients. Finding patients who...
With many pharmaceutical processes needing large water volumes, it’s vital to protect the water against contamination. Storage of purified water at a minimum...
Drug development cost, lengthier development cycles, and identifying a suitable delivery platform were identified as the top three business challenges...
