Pyrogens in pharmaceuticals, medical devices, biotherapeutics and cosmetics can cause fevers in humans and are potentially life-threatening. Yet standard pyrogen detection methods have drawbacks. The Limulus Amoebocyte Lysate (LAL) test only identifies endotoxins, while the rabbit pyrogen test (RPT) endangers animals. Fortunately, the MAT (Monocyte-Activation Tests) alternative covers a much broader range of pyrogens and is completely animal-free. In our insightful webinar you will get a closer look at the whole blood assay, non-endotoxin pyrogens detection, and pyrogen testing in medical devices.
Johns Hopkins Bloomberg School of Public Health & University of Konstanz