Technical Papers

182 Results

In search for “A cell line for Life”

In search for “A cell line for Life”

Content provided by Fujifilm Diosynth Biotechnologies | 23-Nov-2015 | White Paper

The key to developing an elegant, robust and manufacturing-ready process starts during cell line and process development. Early identification of the expression...

Infographic: How to become a pipetting expert

Infographic: How to become a pipetting expert

Content provided by Eppendorf Bioprocess Solutions | 09-Nov-2015 | Infographic

Reverse pipetting, problem liquids, getting the angle right: Pipetting like a pro can be more complex than it seems. The Eppendorf infographic helps you...

Tactical strategies for healthcare M&A success

Tactical strategies for healthcare M&A success

Content provided by UPS UK | 27-Oct-2015 | White Paper

At UPS, our core business is helping companies manage change. We’ve worked with lots of healthcare companies during M&A transitions and have identified...

Screening for growth conditions using micro-Matrix

Screening for growth conditions using micro-Matrix

Content provided by Applikon Biotechnology | 12-Oct-2015 | Case Study

Screening of large number of cell lines, specific media or target drug could be tedious and expensive work. This is also the case for the characterization...

How product design influences an extractable profile

How product design influences an extractable profile

Content provided by Thermo Fisher Scientific | 05-Oct-2015 | White Paper

Biopharmaceutical manufacturers have an obligation to ensure the safety and efficacy of the products they produce. This requirement drives the selection...

Thermo

Rotor exchange simplified

Content provided by Thermo Fisher Scientific | 01-Oct-2015 | White Paper

You may often need to quickly change your centrifuge rotor, for different application requirements. Manual rotor exchange can be time-consuming and tricky,...

New White Paper: Multiplexing in Bioanalysis

New White Paper: Multiplexing in Bioanalysis

Content provided by SGS Life Science Services | 28-Sep-2015 | White Paper

SGS scientists have validated a multiplex, bead-based immunoassay which determines nine cytokines simultaneously per sample, resulting in savings in costs,...

Getting Big Benefits from Small Components

Getting Big Benefits from Small Components

Content provided by AdvantaPure® | 14-Sep-2015 | White Paper

Like a chain, a biopharma transfer system depends on each of its links being strong enough to protect the integrity of the materials being transferred...

When clean is critical

When clean is critical

Content provided by Thermo Fisher Scientific | 31-Aug-2015 | White Paper

Different applications require containers that are at varying levels of cleanliness to avoid contamination. But in order to ensure that your containers...

Accurate control of Glucose and Lactate in bioreactors

Accurate control of Glucose and Lactate in bioreactors

Content provided by Applikon Biotechnology | 10-Aug-2015 | Research Study

The Applikon BioSenz is a unique measuring device specifically developed for measuring & controlling glucose and lactate in bioreactors. Patented heat-flux...

A visual history of cold chain innovation

A visual history of cold chain innovation

Content provided by World Courier | 23-Jun-2015 | Infographic

Download World Courier’s latest piece which shares the story of the changes in temperature-controlled transport and what these trends mean to your business....

How Molded Manifold Assemblies Prevent Leaks

How Molded Manifold Assemblies Prevent Leaks

Content provided by AdvantaPure® | 22-Jun-2015 | White Paper

Pharmaceutical fluid transfer involves many tubing-to-fitting connections, and unfortunately those connections can leak and result in contamination, production...

Efficient bioprocess development

Efficient bioprocess development

Content provided by Eppendorf Bioprocess Solutions | 15-Jun-2015 | Application Note

Bioprocess development requires software that not only monitors and controls process runs, but also integrates design, execution and evaluation of experiments....

Ten Tips for Single-Use Pharma Tubing Selection

Ten Tips for Single-Use Pharma Tubing Selection

Content provided by AdvantaPure® | 08-Jun-2015 | Application Note

Tubing used in biopharmaceutical applications has particular requirements. Among them are the ability to withstand sterilization processes, the delivery...

Using Multiple Techniques in Protein Characterization

Using Multiple Techniques in Protein Characterization

Content provided by SGS Life Science Services | 25-May-2015 | Case Study

The aggregation of biopharmaceuticals is a complex process, for efficient analysis it’s essential to carefully select orthogonal methods to minimize gaps...

Centrifuges designed to simplify performance

Centrifuges designed to simplify performance

Content provided by Thermo Fisher Scientific | 27-Apr-2015 | Infographic

Centrifuges are an integral part of almost every lab. However the set-up of a centrifuge run can be extremely time consuming. Large rotors require assistance...

The Changing Microbial Protein Market

The Changing Microbial Protein Market

Content provided by Information not available | 20-Apr-2015 | Data Sheet

Cobra produced its first protein product in 1995 and has since offered a range of development/cGMP services for mammalian and microbially derived therapeutic...

RAM Resonance Acoustic Mixer, Shaken Not Stirred

RAM Resonance Acoustic Mixer, Shaken Not Stirred

Content provided by Applikon Biotechnology | 20-Apr-2015 | White Paper

The RAM® bench top biological mixer utilizes Resonant Acoustic® technology that applies low-frequency, high-intensity acoustic energy to agitate microbial...

Generating scalable results in micro-bioreactors

Generating scalable results in micro-bioreactors

Content provided by Applikon Biotechnology | 14-Apr-2015 | White Paper

Micro-bioreactors are gaining market share in R&D laboratories. Common applications are strain selection, medium optimization and optimization of cultivation...

BioSep, Scalable & gentle  cell culture perfusion

BioSep, Scalable & gentle cell culture perfusion

Content provided by Applikon Biotechnology | 09-Apr-2015 | White Paper

The Applikon BioSep system is a unique, cell retention device for high-density perfusion processes. BioSep is the ultimate tool for cell culture perfusion...

Single-use systems designed for your workflow

Single-use systems designed for your workflow

Content provided by Thermo Fisher Scientific | 01-Apr-2015 | White Paper

Fluid transfer is an integral part of any biopharmaceutical manufacturing process, and one that can prove challenging. Choosing a customized, single-use...

Demonstrate Biosimilarity of Insulin Biosimilars

Demonstrate Biosimilarity of Insulin Biosimilars

Content provided by SGS Life Science Services | 30-Mar-2015 | White Paper

Download this white paper to learn about two SGS developed assays used to show comparability in reactivity between the reference product and the biosimilar...

Chromatography membrane for polishing applications

Chromatography membrane for polishing applications

Content provided by Pall | 25-Mar-2015 | Application Note

In collaboration with ProBioGen AG, Mustang Q chromatography membrane was evaluated as a polishing step following protein A affinity and cation exchange...

Applikon Biotechnology B.V

Generating scalable results in micro-bioreactors

Content provided by Applikon Biotechnology | 23-Mar-2015 | White Paper

Micro-bioreactors are gaining market share in R&D laboratories. Common applications are strain selection, medium optimization and optimization of cultivation...

Global Ethics - what you need to ensure integrity

Global Ethics - what you need to ensure integrity

Content provided by World Courier | 16-Mar-2015 | White Paper

In a recent World Courier survey, 35% of respondents said that they were aware of bribery in their industries. This may have been acceptable in the past...

Use H₂O₂ sterilization techniques with confidence

Use H₂O₂ sterilization techniques with confidence

Content provided by Thermo Fisher Scientific | 01-Mar-2015 | Application Note

Sterilizing work spaces and containers is an important part of working with sensitive cells. As a highly efficient antimicrobial agent, hydrogen peroxide...

Regulatory Support for Critical Containment

Regulatory Support for Critical Containment

Content provided by Thermo Fisher Scientific | 09-Feb-2015 | White Paper

Choosing the right container is an important factor during pharmaceutical production. Chemicals present within packaging materials can leach into the product,...

Quantitative Analysis of Bioprocess Engineering Parameters

Quantitative Analysis of Bioprocess Engineering Parameters

Content provided by Eppendorf Bioprocess Solutions | 02-Feb-2015 | Data Sheet

This poster characterizes the capabilities of the new Eppendorf BioFlo® 320 bioprocess control station in terms of key process parameters including oxygen...

Meaningful Metrics – A CMO Perspective

Meaningful Metrics – A CMO Perspective

Content provided by Patheon Inc | 26-Jan-2015 | White Paper

Learn about the roles of sponsors and their contract manufacturing organization (CMO) partners regarding metrics, what metrics to measure, how to manage...

Purification process optimization of Fab fragments

Purification process optimization of Fab fragments

Content provided by Pall Biotech | 21-Jan-2015 | Application Note

Fab antibody fragments have been increasingly used for therapeutic applications. Expressed at high yield, they are very specific and lack the Fc portion...

Broad spectrum pyrogen detection according to pharmacopoeia

Broad spectrum pyrogen detection

Content provided by EMD Millipore | 08-Dec-2014 | Application Note

The Monocyte-Activation Test (MAT), which was introduced into the European Pharmacopoeia in 2010, detects pyrogens in pharmaceuticals. It covers a much...

Broad spectrum pyrogen detection according to pharmacopoeia

Broad spectrum pyrogen detection according to pharmacopoeia

Content provided by Merck KGaA, Darmstadt, Germany | 02-Dec-2014 | Application Note

The Monocyte-Activation Test (MAT), which was introduced into the European Pharmacopoeia in 2010, detects pyrogens in pharmaceuticals. It covers a much...

The scalable solution to consistent cell culture

The scalable solution to consistent cell culture

Content provided by Thermo Fisher Scientific | 07-Nov-2014 | Case Study

From research through to full scale bioproduction, you need a system that delivers reliable results, makes effective use of space and is easy to scale...

Directed evolution creates superior CHO cell lines

Directed evolution creates superior CHO cell lines

Content provided by Fujifilm Diosynth Biotechnologies | 03-Nov-2014 | Data Sheet

Directed evolution is an iterative approach where selective pressure is applied to a system to identify variants with desirable characteristics, in this...

5-step guide to Temp-control using passive systems

5-step guide to Temp-control using passive systems

Content provided by World Courier | 20-Oct-2014 | White Paper

Maintaining the strict temperature parameters required to ensure product stability is relatively straightforward in the plant or laboratory setting, where...

Viral-Challenge Studies: Regulatory Requirements

Viral-Challenge Studies: Regulatory Requirements

Content provided by SGS Life Science Services | 13-Oct-2014 | White Paper

The use of viral-challenge studies as POC studies is gaining wider acceptance. This approach accelerates the selection of a safe and effective dose and...

Single-Use Practices for Cleanroom Fluid Transfer

Single-Use Practices for Cleanroom Fluid Transfer

Content provided by AdvantaPure® | 29-Sep-2014 | White Paper

Pharmaceutical and biopharma manufacturers must transfer fluids from room to room quickly with maximum productivity and minimal effort and expense. By...

Turning “Oh No” into “No Problem”

Turning “Oh No” into “No Problem”

Content provided by World Courier | 15-Sep-2014 | White Paper

With all that’s going on in the world right now it’s vital for us all to have plans in place to deal with the unexpected. We need to be prepared individually,...

Bacteria Welcome – BioBLU® f Single-Use Vessels

Bacteria Welcome – BioBLU® f Single-Use Vessels

Content provided by Eppendorf Bioprocess Solutions | 15-Sep-2014 | Data Sheet

The BioBLU 0.3f and BioBLU 1f Single-Use Vessels allow microbial process development at the highest level. These rigid wall stirred-tank single-use vessels...

Analysis & Control of Particles in Biologics

Analysis & Control of Particles in Biologics

Content provided by SGS Life Science Services | 08-Sep-2014 | White Paper

A key challenge for companies developing biologics is the control of particles in the product formulation. Regulatory authorities require information on...