White Paper
Seed Train Intensification Using High Cell Density Cryopreservation and Specially-designed Expansion Medium
![Seed Train Intensification Using High Cell Density Cryopreservation and Specially-designed Expansion Medium](/var/wrbm_gb_food_pharma/storage/images/_aliases/wrbm_product_file/publications/pharmaceutical-science/biopharma-reporter.com/resources/bioreactors/seed-train-intensification-using-high-cell-density-cryopreservation-and-specially-designed-expansion-medium/11595682-1-eng-GB/Seed-Train-Intensification-Using-High-Cell-Density-Cryopreservation-and-Specially-designed-Expansion-Medium.png)
Strategies such as process intensification have the potential to create shorter lead times, reduce plant footprint, increase flexibility, and reduce COGs.
Upstream processes can be intensified using a number of strategies that can deliver significant improvements in speed, flexibility, and reliability. In this white paper, we explore two of these approaches – High cell density cryopreservation (HCDC) and the use of a perfused seed train including a specially-designed expansion medium.