Application Note
Optimization, Validation and Implementation of Retroviral Retentive Filters for Production of Adeno-Associated Virus (AAV)
Viral contamination is a risk for all biotechnology products. Recent studies have shown that viral retentive filtration is one of the most robust steps in removing all types of viruses.
In this study, we focused on the initial development process of the retroviral-retentive Viresolve® NFR filter. In order to evaluate the efficacy of the Viresolve® NFR filter for removal of large viruses from AGTC’s AAV vectors, a preliminary viral clearance study was performed.
