Bioprocess Optimization by MS Integration
With its comprehensive data management the Eppendorf DASware® Software Suite allows seamless integration of a Thermo Scientific® Prima® dB Mass Spectrometer (MS) enabling online calculation of key fermentation operating values.
The following application note describes how MS integration was implemented to optimize an isobutanol production process. Using OPC communication the real-time MS results were sent to the DASGIP® Control System. Within the control system, the fermentation runtime data and the MS results were charted and transferred to the data historian with synchronized time stamps.