This white paper describes process modeling and compares the process economics of a conventional upstream process versus three perfused seed train alternatives in combination with either a conventional fed-batch or high-seed fed-batch bioreactor.
- Upstream Intensification – Enabling Perfusion Processes with Cell Retention Technologies
- Seed Train Intensification Using High Cell Density Cryopreservation and Specially-designed Expansion Medium
- Shifting the Biomanufacturing Paradigm
- Mitigating Risks Associated with Cell Culture Media Preparation and Handling