Antibody-Drug Conjugates

Lonza expands manufacturing sites for larger ADC payloads

16-Oct-2018 By Maggie Lynch

Lonza Pharma & Biotech will expand two of its manufacturing sites to reach the capabilities necessary to produce compounds bio-conjugates through to commercialization.

Merck biosimilar made available on the US VA National Formulary

12-Oct-2018 By Maggie Lynch

The US Department of Veteran Affairs awarded a national contract for Merck’s biosimilar to be available on its National Formulary.

Daiichi-Merck partnership lines up Keytruda combo therapy

09-Oct-2018 By Maggie Lynch

Daiichi Sankyo announced it has entered into a clinical trial collaboration agreement with Merck & Co. to evaluate an investigational lung cancer treatment.

Regeneron and Sanofi receives first US FDA approval for PD-1 treatment

03-Oct-2018 By Maggie Lynch

The US FDA approved the first drug created by the 2015 partnership between Regeneron and Sanofi to research and develop immuno-oncology therapies.

Partnership to provide oncology portfolio with a translational platform

19-Sep-2018 By Maggie Lynch

Mitra Biotech and Glenmark Pharmaceuticals have partnered to advance research on Glenmark’s immuno-oncology treatments using Mitra’s platform.

US FDA approves expanded label for Merck’s Keytruda as first-line treatment for NSCLC

22-Aug-2018 By Maggie Lynch

The US FDA has approved an expanded label for Merck’s Keytruda in combination with pemetrexed and platinum chemotherapy.

Daiichi Sankyo and Glycotope reach agreement for “first-in-class” ADC

03-Aug-2018 By Maggie Lynch

Daiichi Sankyo and Glycotope have signed a licensing agreement to develop an antibody-drug conjugate that enables tumor-specific binding to TA-MUC1.

ADC Bio: Biotech may 'hold the key' to innovation adoption

08-Jun-2018 By Flora Southey

CDMOs need to respond to biotech innovation at an R&D level to improve efficiency in antibody-drug conjugate manufacturing, says ADC Bio.

The Golden Ticket: Sanofi, Meditope initiate research collaboration to explore bioconjugation tech

09-May-2018 By Melissa Fassbender

Sanofi has awarded Meditope Biosciences a BioLabs’ “Golden Ticket” to support the development of its bioconjugation platform and create new antibody-based therapeutic constructs.

ADC Bio’s $1.5m investment to boost antibody-drug conjugate manufacturing

01-May-2018 By Flora Southey

ADC Bio has announced receipt of a £1.14m investment it says will help reduce antibody-drug conjugate manufacturing time and costs.

Bio-Separation: Our outgoing editor looks back over 5 years

13-Apr-2018 By Dan Stanton

Biopharma-Reporter editor Dan Stanton is finally packing his buffer bag and moving upstream.

News in Brief

Abzena remodels ADC facility in Pennsylvania

28-Mar-2018 By Staff Reporter

Abzena has equipped its $5m Pennsylvania bioconjugation suite with Sartoius and GE Healthcare single-use equipment.

Xencor extends ‘plug-and-play’ deal with Selexis, signs four mAbs

28-Feb-2018 By Flora Southey

Xencor and Selexis will extend their strategic partnership with the signing of four commercial license agreements to advance XmAb bispecific antibody drug candidates.

Concurrent purification approach could cut ADC manufacture by 25%, ADC Bio

16-Feb-2018 By Dan Stanton

ADC Bio has developed a concurrent conjugation and antibody purification process, not reliant on Protein A capture resin.

ImmunoGen closing MA plant: 20 jobs to go, $20m in savings

15-Feb-2018 By Staff Reporter

ImmunoGen says it is shifting drug conjugate manufacturing and quality testing to an outsourcing model and will close its Norwood facility.