Regulus’ microRNA wins potential $750m Sanofi deal
Regulus Therapeutics’ microRNA satellite technology has won the firm its biggest deal to date with French drugmaker Sanofi-Aventis agreeing a development accord worth up to $750m (€606m).
Supercritical drug delivery patent awarded to Aphios
Aphios has been awarded a patent that details an improved process to formulate a polymer-based drug delivery nanotechnology platform. The method offers a more sustainable, consistent administration of therapeutics with less dosage-dependent side effects.
ViroPharma files with FDA to up HAE drug production
ViroPharma is seeking permission from the Food and Drug Administration (FDA) to increase production of Cinryze to an industrial scale as part of its ongoing expansion activities.
US supplier SAFC recently expanded its liquid cell culture reagents in response to growing biomanufacturing industry demand.
Researchers recycle TV material into drug delivery aid
Researchers believe they have found a way of transforming a key element of liquid crystal display (LCD) televisions into a substance that can be used in pills and dressings designed to deliver drugs to certain parts of the body.
Minapharm buys CMO ProBioGen for €30.4m
Egypt-based Minapharm has acquired 95 per cent of CMO ProBioGen for a possible total of €30.4m ($37.6m).
AMRI buys Hyaluron to enter prefilled syringe market
AMRI has acquired Hyaluron for $27m (€22m) to enter the prefilled syringe market and expand the customer base for its existing operations.
BioScale wins funding to develop protein analytics tech
BioScale has secured $25m (€21m) to fund commercialisation of its ViBE protein analytics systems.
Novavax & Cadila open Indian vaccine facility
Cadila Pharmaceuticals and Novavax have completed construction of their joint venture vaccine manufacturing plant in Dholka, India.
Cellectis and Lonza form biomanufacturing partnership
Lonza is to collaborate with France’s Cellectis SA for the development and commercialisation of a bioengineered cell line.
CRL shareholder criticises and opposes WuXi deal
CRL shareholder Jana Partners has said the attempt to buy WuXi PharmaTech is the “wrong path” and it will vote against the deal.
Quintiles predicts PI3K demand and boosts assay offering
US CRO Quintiles expands PI3K assay offering, predicting increased drug industry demand for expertise in key survival pathway in era of personalised cancer treatments.
Genzyme adding more manufacturing experience and resignations at Uluru and Par – People on the move
in-PharmaTechnologist presents its latest round up of movements in the pharma sector, including Genzyme adding more manufacturing experience and resignations at Uluru and Par.
Philips and RXI partner to research RNAi delivery
Philips and RXi Pharmaceuticals have formed a research agreement to investigate combining their technologies for delivery of RNA interference (RNAi).
IAG raises $52m to establish Russian preclinical GLP CRO
Investors are funding the creation of a RUB1.6bn ($52m), 10,000 sq m preclinical Russian CRO to fill the gap in the nation’s development chain and undercut western prices by 40 per cent.
NAFDAC keen on new SMS anti-counterfeit results
An anti-counterfeiting pilot project in Nigeria, which uses a mobile authentication service (MAS) to validate genuine medication, has completed a 100-day pilot phase. Preliminary results suggest the scheme is well on the way to becoming an effective defence...
Shasun Chemical reports net profit for year
Indian API manufacturer Shasun Chemicals and Drugs turned a previous loss into profit for Q4 of this year as it seeks to make a dent in the biosimilar manufacturing sector.
Large pharma to boost CMOs’ biologics business; report
CMOs are set to gain biologics business and capacity in the coming years as large pharma increasingly outsources to cut costs and speed development, according to a report published today.
Natural drug delivery system aids cancer therapeutics
New research could make it possible for scientists to use silicon particles as an effective drug delivery system that enables fragile small interfering RNA (siRNA) based drugs to be directly transported to the disease’s location.
Irish pharmaceutical company Elan says most potential investors are positive about proposal to spin-off drug delivery unit.
Cheaper insulin production proposed for emerging markets
Researchers have developed an alternative, cheaper method of producing insulin to help increase availability in emerging markets.
Cevec licenses CAP-T cell expression tech to Pevion
Cevec has exclusively licensed its transient CAP-T cell expression technology to Pevion for the manufacture and commercialisation of a protein antigen to vaccinate against an infectious disease.
Apotex launches generic Lipitor in Canada
Generics firm Apotex has launched a non-branded version of Pfizer’s mega-blockbusting cholesterol drug Lipitor in Canada
Almac teams on X-ray data analysis; US plant nears completion
Almac hopes University College Cork solid state chemistry accord will bypass crystallisation hurdles and accelerate drug development.
DSM: XD scale-up can cut drug production costs
DSM Biologics says successful XD tech expansion paves way for smaller bioreactors that lowers cost of production facilities and, ultimately, of bio-drug manufacture.
CRAMS growth helps Jubilant in fiscal 2010
International demand for contract manufacturing helped India’s Jubilant Organosys finish fiscal 2010 with a quarter of growth.
DSM joins with Australian government for biologics plant
DSM Biologics has entered into a partnership with the Australian government to build a 70,000 sq ft biopharmaceutical contract manufacturing facility.
GBI, Hyprocell collaborate to offer cell line development
CMO Goodwin Biotechnology Inc (GBI) is collaborating with Hyprocell to help clients that need manufacturing services but have a sub-optimal cell line producing low concentrations.
New Xcellerex CEO targets growth in revenues, clients
The incoming Xcellerex CEO plans to move the company from validation to penetration, boosting revenues and client base, and invest in the contract manufacturing side of the business.
ACRO funds research into CROs’ role in drug development
ACRO is aiming to increase recognition and analysis of the value CROs bring to drug development, spanning their role as strategic partners throughout the process, by funding academic research.
Mircofluidics launches continuous nanocrystallisation tech
Microfluidics chose Interphex 2010 in New York, US to unveil a new processing technology that it claims can help manufacturers save time and money by switching from batch to continuous particle production.
ATMI introduces disposable bioreactor
ATMI is using Interphex 2010 to launch the Integrity PadReactor, a disposable bioreactor designed to provide a highly scalable entry point in its line of mixing and process manufacturing systems.
Ajinomoto launches scalable complex peptide synthesis
Ajinomoto AminoScience has launched AjiPhase, a peptide synthesis service which makes it practical and efficient to produce and scale up products that were previously considered too complex.
Grant given to develop continuous flow crystallisation
A project bringing together researchers from academia and pharma companies, including GSK and AZ, has received a £709,000 ($1.09m) grant to create crystals using continuous flow production.
Streamlining of Indian supply chain needed to cut costs
Rising use of biologics and a tax initiative will drive the streamlining of Indian supply chains, helping companies to deliver drugs at affordable prices, according to PwC.
Hikma to take control of Algerian joint venture
Hikma is to take full control of its Algerian joint venture in an $18.5m (€13.6m) deal, continuing its expansion in the region.
DiscoveRx adds GPCR platforms
DiscoveRx has added GPCR platforms to its portfolio, enhancing its ability to provide information on a compound’s mode of action, activated receptor recycling and efficacy in animal models.
DPT, NextPharma and Vetter update on sterile production expansions
The drug industry will gain new options for sterile contract development and manufacturing in the near future with DPT Laboratories, NextPharma and Vetter each working on new dedicated units.
Charter Medical launches single-use Bio-Pak culture bags
US group Charter Medical says its new-single use culture bags provide a stable environment that enhances cell growth and viability.
Metrics adds melamine testing
Metrics is offering melamine detection testing services for starting materials to help clients ensure their products are free from contamination.
Anticancer APIs drive ScinoPharm gains in 2009
Contract manufacturing organization (CMO) ScinoPharm says strong anticancer API sales and growing demand in Europe and Asia were key to record performance in 2009.
PPD increases focus on vaccines and biologics
PPD has added capabilities at the facility acquired from Merck & Co and improved integration of other sites to create its Vaccines & Biologics Center of Excellence, a single provider of multiple laboratory services.
IRL and Epichem partner to serve Australasian market
IRL and Epichem have entered into a strategic alliance to provide the Australasian pharma market with services from drug discovery through to cGMP production.
Pall teams with Sotax on filters; reports biopharma biz strong in Q2
Industrial filtration specialist Pall and testing firm Sotax say their new co-marketing deal is only first stage of planned pharmaceutical industry certification solutions partnership.
NexACT shows preclinical SR potential
CRO NexMed says new data from preclinical trials show that its NexACT delivery technology can act as a sustained release “depot” for drugs like insulin and taxol.
Millipore launches Milliflex Quantum for rapid microbial detection
Millipore has expanded its microbial detection offering with Milliflex Quantum which, it says, enables manufacturers to respond to contamination issues earlier in the drug and vaccine production process.
Pfizer and Tekirma team on siRNA delivery
US drug giant Pfizer will assess Tekimra Pharmaceuticals’s stable nucleic acid-lipid particle (SNALP) platform for the delivery of siRNA drugs.
Compugen creates system to predict peptide delivery
Compugen has developed a computer-based, in silico system which can assist drug delivery research by identifying peptides that have the potential to penetrate cell membranes.
Sigma adds big name small molecules to portfolio in Pfizer deal
Drug researchers will have greater access to some top selling molecules, including currently patented compounds atorvastatin, sildenafil and celecoxib, thanks to Sigma Aldrich’s new bioactives deal with US drug major Pfizer.
China to build ‘one of largest biologics CMOs in Asia’
The Chinese government is supporting a $100m (€73m) project to build a contract biologics production facility in Beijing, which, by some measures, would be the largest in Asia.