Sartorius develops ‘game changing’ chromatography product
Sartorius says it is bringing a scalable, ready-to-use disposable Protein A membrane to market, triggering a paradigm shift in the monoclonal antibody capture step by overcoming nearly all the limitations of packed bed chromatography.
Biopharmaceutical companies who use packed bed chromatography for mAb capture often suffer from low productivity, higher costs, and laborious operations.
Sartobind Rapid A. a one-batch, one membrane approach, can save up to 30% on overall process cost in clinical scale manufacturing and produces data faster with rapid cycling and high binding capacity to perform lifetime studies within one day, said the developer.
The ready-to-use membrane product makes it possible to bypass column-packing, cleaning validation and storage, reducing non-productive activities around column use by 80%, said the company.
