News & analysis on the clinical development and manufacture of large molecule drugs
Tech to reduce the number of biopharma manufacturing process steps
By Jane Byrne
- Last updated on
3M Health Care recently launched the 3M Polisher ST, a single-use AEX solution designed to replace reusable AEX polishing column for biologic drug manufacturing.
The developer said Polisher ST improves the biopharma manufacturing workflow by reducing the number of processing steps thereby helping to improve process economics.
A synthetic, fully encapsulated, single-use membrane chromatography solution, it contains two complementary AEX-functional media: a quaternary ammonium (Q) functional nonwoven and a guanidinium-functional membrane.
The equipment can be used in continuous bioprocessing: It is a single-use technology designed as a cost-efficient option to increase biomass production in therapeutic recombinant protein processes in all operating conditions; and to replace downstream AEX polishing column in fed batch and/or continuous manufacturing.
"3M Polisher ST is designed as a next-generation bioprocessing solution for process intensification in both large, dedicated product sites and small multi-product manufacturing facilities," said Robert Befidi, Jr, division vice president, 3M Separation and Purification Sciences. "This product will be particularly suitable for facilities of the future which will be smaller in size and capable of producing significantly higher product volumes.”