CMAB completes antibody development for QureBio

By Ben Hargreaves

- Last updated on GMT

(Image: Getty/Hywards)
(Image: Getty/Hywards)

Related tags CMAB Biopharma QureBio China Single-use bioreactor

The Chinese CDMO takes bispecific antibody through to IND-stage in nine months.

CMAB Biopharma, a Chinese contract development and manufacturing organization based in Suzhou, teamed up with QureBio to develop Q-1802.

The bispecific antibody is now ready for an investigational new drug (IND) application with the US and China, after nine months of development by CMAB.

The CDMO carried out all of the development work in-house, utilizing its integrated platform. As part of the process, CMAB created three 200L batches using single-use bioreactors, with the last batch expected to be fully released in two months.

QureBio is Chinese biotech based in Shanghai that was established in 2017. Earlier this year, the biotech secured ¥10M ($1.4m) in a financing round to develop two preclinical projects, Q-1802 and Q-1801.

QureBio’s Q-1802 is a bispecific antibody that is being tested as a treatment of solid tumors, such as gastric cancer. In China, gastric cancer is one of the leading causes of death​. While Q-1801 targets the tumor microenvironment.

Yejie Du, QureBio’s head of CMC, noted that the two companies would work together to pursue dual IND filings in China and the US, as well as to take its ‘major products’ into clinical trials.

Related news

Show more

Related products

show more

Trends in Biopharmaceutical Raw Material Selection

Trends in Biopharmaceutical Raw Material Selection

Actylis – The Partner of Choice | 31-Jan-2023 | Business Advice

Join us as our in-house experts, along with Cecile Bellamy from Pfizer, discuss current and future trends in biopharmaceutical raw material selection.

eBook: mRNA prospects and scale-up solutions

eBook: mRNA prospects and scale-up solutions

Thermo Fisher Scientific - Biosciences | 01-Jan-2023 | Insight Guide

This mRNA eBook was created by Thermo Fisher Scientific, in collaboration with Genetic Engineering & Biotechnology News (GEN), to provide you with...

Create Better Biologic Treatments with Catalent

Create Better Biologic Treatments with Catalent

Catalent | 06-Dec-2022 | Product Brochure

Your biologics possess a high level of complexities and technical challenges. That’s why development is key to ensuring the successful delivery of your...

Related suppliers

Follow us

Products

View more

Webinars