Selexis and Symphogen expand partnership to progress two mAbs

By Ben Hargreaves contact

- Last updated on GMT

(Image: Getty/Media Point Inc
(Image: Getty/Media Point Inc

Related tags: Selexis, Symphogen, Monoclonal antibodies

Selexis and Symphogen have announced that the latter has submitted INDs for clinical programmes to progress two mAbs using Selexis’ platform.

The investigational new drug applications (INDs) are for Sym022 and Sym023, which are being investigated for potential use as treatments for locally advanced/unresectable or metastatic solid tumours or lymphomas that are refractory to available therapy or for which no standard therapy is available.

Selexis revealed that Symphogen will utilise its Selexis Genetic Elements (SGE) technology to advance the two potential drug candidates.

This comes after Symphogen had previously, in 2016, used the SGE technology to advance Sym015, a novel antibody mixture containing two humanised monoclonal antibodies (mAbs), through to clinical development, according to the companies​.

“Selexis and Symphogen have had a great working relationship over the past several years and we are proud to expand our partnership through these two additional programs based on the success they have had using our SUREtechnology platform,”​ said Marco Bocci, Selexis vice president, licensing and business development.

Symphogen has been working with Selexis’ SUREtechnology ​platform from 2014, while earlier this year​ Compugen also announced it would work with the technology to generate research cell banks and develop its immuno-oncology products.

With the number of its partnerships increasing, Selexis announced that it would invest to improve the delivery times of its research cell banks, in April 2018​.

Related topics: Upstream Processing, Pipelines, Cell lines

Related news

Related products

show more

rAAV Production in BioBLU® Single-Use Vessels

rAAV Production in BioBLU® Single-Use Vessels

Eppendorf for Bioprocess – Solutions that grow with you | 25-Jun-2019 | Application Note

Rising interest in gene therapy-based applications leads to increasing demands in scalable production systems for viral vectors. Find out how Cevec Pharmaceuticals...

Small-Scale Cell Culture Perfusion Process

Small-Scale Cell Culture Perfusion Process

Eppendorf for Bioprocess – Solutions that grow with you | 29-Mar-2019 | Application Note

Perfusion cell culture processes promise advantages for industrial bioprocessing, like saving space, increasing volumetric productivity, achieving more...

Cultivation of 3D Cell Aggregates in Perfusion

Cultivation of 3D Cell Aggregates in Perfusion

Eppendorf for Bioprocess – Solutions that grow with you | 17-Sep-2018 | Application Note

3D cell aggregates are of great interest for applications like disease modeling and manufacturing of stem cell-based products. Read more about the cultivation...

Nifty Biosimilar

Nifty Biosimilar

UGA Biopharma | 13-Mar-2018 | Research Study

Aflibercept (Zaltrap®) is a recombinant fusion protein with complex post-translational modifications. Therefore deep understanding of biosimilar development...

Related suppliers

Follow us


View more