Cell therapy demand means CMOs need to up their capabilities, PharmSource

By Dan Stanton contact

- Last updated on GMT

GettyImages/Meletios Verras
GettyImages/Meletios Verras
There is a lack of third-party capabilities in the autologous cell therapy space says the new editor of PharmSource ahead of this year’s Interphex Convention.

Industry will converge on The Javits Center in New York City next week to discover the latest technologies and movements within the biopharma manufacturing space.

According to Fiona Barry, the new editor of PharmSource – a GlobalData product – on of the most hotly anticipated topics at this year’s show will be cell therapies, driven by the approvals of Novartis’ Kymriah (tisagenlecleucel)​ and Kite/Gilead’s Yescarta​ last year.

This is creating demand for contract manufacturing organisations (CMOs) which will need to fill gaps in their capabilities, especially for autologous therapies, Barry told Biopharma-Reporter.

Manufacturing capabilities needed for autologous cell therapies are not yet common, and most CMOs are not yet competent,”​ she said. “Our research shows there only approximately 30 companies involved in contract manufacturing autologous cell and tissue therapies​.”

There has been some action by CMOs to increase their cell therapy offering over the past year. Swiss manufacturer Lonza acquired PharmaCell in June​, for example, but most manufacturing, for now, is being done in-house.

Therefore CMOs need to build competency in a range of services to support reproducible production methods for autologous cell therapie, said Barry, including “growing human cells, assays, automation, and even in filling the skills gap among staff.”

Furthermore, there is a growing opportunity for other service areas to help support this growing space.

“Supply chain logistics are more important than ever for these therapies, because they represent the patient’s own irreplaceable cells and are often a last resort treatment,”​ Barry added. “Quality testing is also crucial for this vulnerable population.”

Related news

Show more

Related products

show more

dPCR Case Study

dPCR Case Study

CellCarta | 08-Aug-2022 | Case Study

Streamline your adoptive cell therapy program with digital PCR. Our team has a unique expertise in digital and quantitative PCR to support you in ensuring...

The Reagents Behind Much of Molecular Biology

The Reagents Behind Much of Molecular Biology

Thermo Fisher Scientific | 25-Jul-2022 | Case Study

The ability to amplify, modify and fabricate DNA is fundamental to modern molecular biology. Why do so many researchers take their constituent parts for...

Microsampling in Early Phase Drug Development

Microsampling in Early Phase Drug Development

Altasciences | 10-May-2022 | Technical / White Paper

Microsampling significantly lessens the volume of blood and plasma/serum that is collected and analyzed to determine circulating concentrations of therapeutic...

Consideration and Options for Prefilled Syringes

Consideration and Options for Prefilled Syringes

Baxter BioPharma Solutions | 16-Feb-2022 | Technical / White Paper

Convenience, product differentiation, and less waste are great reasons for developing a product in a prefilled syringe. Baxter’s whitepaper describes the...

Related suppliers