JV makes ‘stability timer’ logistics tech to protect cell and gene therapies

By Flora Southey contact

- Last updated on GMT

GettyImages/Nastco
GettyImages/Nastco
The US Patent and Trademark Office has granted a notice of allowance for ‘shelf life’ timer technology used to protect time-sensitive biologic materials in transit.

BioLife Solutions and Savsu Technologies said the technology will be incorporated into Savsu’s evo.is cold chain software offering. The patent – to be issued on April 10, 2018 – covers Biologic stability, delivery logistics and administration of time and/or temperature sensitive biologic based materials​ (9,939,422 and 9,939,423).

The US-headquartered firms formed a joint venture (JV) in 2014 to develop precision thermal shipping containers under Savsu’s evo brand.

A Savsu spokesperson told us the patent covers a payload “stability timer” – also known as a “shelf life” timer in the evo.is cold chain offering – to help transport and protect high value payloads, such as cell and gene therapies.

The timer tracks the remaining stability time and informs clinicians and relevant parties via a messaging system. 

“Manufactured, personalized cell therapy doses are temperature- and time-sensitive payloads that must be administered to the patient within a validated stability period or shelf life,” ​the spokesperson explained.

It is easy for busy employees in hospital receiving areas to set aside or overlook a package that has a time sensitive payload, the spokesperson told us.

However, in the event of a delay in transit, the timer provides a “helpful reminder,” ​so that “all parties can evaluate the situation and possible corrective actions in relation to the time left on the timer.”

Pack-out errors

The patent also detects cold packs and the biologic payload container to help reduce pack-out errors.

“Alerting pack-out technicians that the shipping container is not packed out correctly could mean the difference between a cancer patient being administered a viable CAR T-cell therapy vs. receiving cells that were dead on arrival,” ​said the spokesperson.

The joint venture has received two USPTO patients to date and has 11 additional patent applications pending, covering hardware and software.

Related news

Related products

show more

dPCR Case Study

dPCR Case Study

CellCarta | 08-Aug-2022 | Case Study

Streamline your adoptive cell therapy program with digital PCR. Our team has a unique expertise in digital and quantitative PCR to support you in ensuring...

The Reagents Behind Much of Molecular Biology

The Reagents Behind Much of Molecular Biology

Thermo Fisher Scientific | 25-Jul-2022 | Case Study

The ability to amplify, modify and fabricate DNA is fundamental to modern molecular biology. Why do so many researchers take their constituent parts for...

Microsampling in Early Phase Drug Development

Microsampling in Early Phase Drug Development

Altasciences | 10-May-2022 | Technical / White Paper

Microsampling significantly lessens the volume of blood and plasma/serum that is collected and analyzed to determine circulating concentrations of therapeutic...

Seasonal Vaccine Manufacturing

Seasonal Vaccine Manufacturing

Baxter BioPharma Solutions | 16-Feb-2022 | Technical / White Paper

The production of seasonal vaccines, such as those for influenza, presents unique challenges to manufacturers due to the necessary time constraints resulting...

Related suppliers

Follow us

Products

View more

Webinars