Continuous chromatography and single-use filtration at BPI Europe

By Dan Stanton contact

- Last updated on GMT

Related tags: Biotechnology

Pall Corporation, GE Healthcare and LEWA Process Technologies showed off their latest downstream offerings to Biopharma-Reporter in Amsterdam last week.

This year’s Bioprocessing International (BPI) European Summit took place in Amsterdam, The Netherlands, last week, and amid the hubbub of cell line innovations and fancy fermenters stood the latest in downstream bioprocessing tech.

Pall Life Science boasted about its Cadence Acoustic Separator which can be used to clarify fed-batches of CHO cell cultures, which senior separation technology specialist Marco Koppe said can also be used for continuous bioprocessing which he said is “becoming more and more important”​ within the industry.

The tech is available for lab-scale bioproduction but a large-scale GMP version will be available later this year.

Similarly, German tech firm LEWA was displaying its chromatography system for the continued purification of monoclonal antibodies. Working with partner ChromaCon, the Contichrom CUBE Combined system system has a twin-column configuration for continuous purification within a GMP system.

“The system you see here has a maximum flow rate of 600ml/minute and with a 10cm Protein A column – two of them of course – you can actually produce up to 1.5kg of monoclonal antibodies per day,”​ sales director for Europe and Asia Flemming Carlsen told us

“This is fitting for quite a lot of the expected new perfusion systems that will deliver the high titre of mAb in pilot and maybe production scale.”

Meanwhile GE Healthcare showcased its AKTA Readyflux system, the filtration companion to its AKTA chromatography system. The tech is a single-use system designed for either a hollow-fibre or cassette format.

Related news

Show more

Related products

show more

Connectivity & Integration in Biomanufacturing

Connectivity & Integration in Biomanufacturing

Wheeler Bio | 17-Nov-2022 | Technical / White Paper

As the Pharma 4.0 initiative sets a new industry paradigm, more biomanufacturing companies are asking how they can design and build facilities that apply...

GMP manufacturing of buffers and liquid blends

GMP manufacturing of buffers and liquid blends

Actylis – The Partner of Choice | 16-Nov-2022 | Technical / White Paper

Actylis manufactures buffers, process solutions, cleaning solutions, Water for Injection (WFI) for further processing, and custom liquid blends in compliance...

Custom manufacturing of protease inhibitor PMSF

Custom manufacturing of protease inhibitor PMSF

Actylis – The Partner of Choice | 09-Nov-2022 | Technical / White Paper

By combining 75+ years of manufacturing and sourcing expertise, Actylis provides a wide portfolio of GMP ingredients to the pharma & biopharma market,...

Scalability, Quality, and Speed with Transposons

Scalability, Quality, and Speed with Transposons

Wheeler Bio | 20-Oct-2022 | Technical / White Paper

To solve for the significant bottlenecks often presented by conventional cell line development processes, this article discusses how Wheeler Bio is leveraging...

Related suppliers

Follow us


View more