Pall hopes to have manufacturing in the bag

By Nick Taylor

- Last updated on GMT

Related tags: Risk, Disposable, Pall

Pall Life Sciences has launched its Allegro 3D biocontainers, which have been designed to improve the performance of the company’s large-scale, single use manufacturing systems.

The product is a single-use film container that can be employed in upstream and downstream purification process steps of the production of biotherapeutic molecules.

Pall’s 3D biocontainers are available in 100L, 200L and 500L sizes, which are all made from the same material. This allows companies to easily scale-up production and get the benefits of single-use systems at each step.

Helene Pora, Pall’s senior director of single-use systems, said: "Single-use systems provide a greater assurance of sterility and purity by reducing microbial and cross contamination risks. They also reduce capital investment costs for facilities and equipment, costs associated with cleaning and cleaning validation, and they reduce lead times to help get drug products to market faster​.

In applications that process hazardous materials, such as cytotoxic drugs and potent biological materials, closed disposable systems offer additional protection by isolating operators from potential dangers​."

Pall claims its biocontainers are more robust and make it easier to recover large fluid volumes, with all but 100ml being drained regardless of the size of the containers.

In addition each biocontainer has a sampling port and two inlets. The second inlet port can be used to insert a sensor, enabling process monitoring, or as an extra site to input material through.

These can either be at the top or bottom of the container, allowing for it to be filled in a manner that suits the users need.

Related topics: Upstream Processing

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