SUBSCRIBE

Breaking News on Biopharmaceutical Development & Manufacturing

Headlines > Upstream Processing

Abzena to make wet-AMD antibody drug candidate for UCL at US plant

21-Feb-2017 - Abzena Plc has been contracted to make an antibody drug candidate for wet age-related macular degeneration by developers at University College London.

Bio-outsourcing share to drop as Big Pharma invests heavily in-house, analyst

15-Feb-2017 - CMOs will struggle to compete with large in-house capacity investments, according to Results Healthcare which predicts a decline in outsourced biomanufacturing.

Thermo Fisher bags single-use bioreactor tech partner Finesse

14-Feb-2017 - Thermo Fisher Scientific says it is buying Finesse Solutions, its long-term supplier of measurement and control solutions for bioprocessing applications.

Novasep’s €27m viral vector plant to create up to 100 Belgian jobs

14-Feb-2017 - The new viral vector production facility will contain two GMP suites equipped with single-use bioreactors ranging from 200L to 2,000L, says Novasep.

Catalent running its biologics business at over 90% capacity

08-Feb-2017 - Catalent is struggling to keep up with demand for its biomanufacturing services, but a third production train will open up more capacity from October.

Roche: 'Largest biomanufacturing capacity across the industry' to get bigger

07-Feb-2017 - Roche says it will continue to expand its biologics manufacturing capacity while reducing its small molecule network.

GE Healthcare's 'Cell line agnostic' FlexFactory to boost Turkish biosimilars business

07-Feb-2017 - Arven will use GE Healthcare’s FlexFactory manufacturing platform to increase capacity at its mammalian-cell based bioproduction facility in Kirklareli, Turkey.

TapImmune improves T-cell vaccine formulation ahead of Ph II trials

03-Feb-2017 - TapImmune has completed a multi-gram scale-up and GMP manufacturing of its lead product as it prepares for various Phase II studies.

FINANCIAL REPORT

Thermo Fisher's cautiously optimistic outlook for 2017

02-Feb-2017 - Thermo Fisher Scientific, Inc. saw revenue grow 8% in 2016, mostly due to acquisitions of new Chromotography and mass spectrometry tech and expanding its Bioproduction.

Novo Nordisk Foundation grants $17m for pharma fermentation pilot plant

01-Feb-2017 - The Novo Nordisk Foundation has awarded a DKK118m ($17m) grant to fund development of a fermentation pilot plant for cell line scale up experiments at the Technical University of Denmark....

Single-use once again growth engine for Sartorius

31-Jan-2017 - Sartorius reported a 22% year-on-year growth in sales in its bioprocessing division, driven by continued demand for single-use systems.

Patented GE bioreactor bag boasts of 214m CHO cells/mL in perfusion mode

31-Jan-2017 - GE Healthcare says a new inflatable bioreactor bag configured in perfusion mode can achieve a cell density over four times that of the current industry standard.

Biocon wins $68m Malaysian contract for biosimilar insulin and pen supply

26-Jan-2017 - Biocon has been awarded a three-year contract to supply recombinant human insulin formulations made at its Malaysian facility to the country’s Ministry of Health.

FDA hits UK state-owned CDMO with warning over leukemia drug production

25-Jan-2017 - Porton Biopharma says it is undergoing a manufacturing review to address US FDA concerns about the production of Jazz Pharmaceuticals’s orphan drug Erwinaze.

ADMA to buy US Biotest plant and fix problems that derailed RI-002

24-Jan-2017 - ADMA Biologics has agreed to buy production assets from the CMO whose manufacturing deficiencies saw the US FDA reject its lead candidate, RI-002, last year.

Biopharma survey: Shortage of bioprocessing talent key threat to sector

20-Jan-2017 - Industry is struggling to find and develop skilled bioprocessing workers according to respondents to NIBRT’s biopharma trends survey.

UPDATED: UCART19

Servier universal CAR-T therapy outsourced to Belgian CDMO

18-Jan-2017 - Servier has recruited CDMO MaSTherCell SA to manufacture its universal CAR-T candidate UCART19, licensed from the biotech Cellectis as an off-the-shelf cell therapy for leukemia.

Irvine Scientific introduces xeno-free T cell growth medium

18-Jan-2017 - Irvine Scientific has launched what it says is the first available chemically-defined, animal component-free medium for T cell culture.

Exclusive interview

Single-use bioreactors: 2,000L a ceiling, says new BPSA board member

17-Jan-2017 - The majority of biomanufacturers use single-use systems at least in the development stage says Entegris’ Eric Isberg, but scaling-up will always be a challenge.

AGC boasts 44,000L of biomanufacturing capacity on back of recent M&A

11-Jan-2017 - After buying two CMOs, Japanese glassmaker AGC has made “a full-fledged launch” into the biologics manufacturing space and says it will consider further M&A opportunities.

Shire selling Baxalta site in Austria once earmarked to make hemophilia drug

06-Jan-2017 - Shire has confirmed it is selling a former Baxalta manufacturing site in Austria once earmarked for a €138m ($145m) expansion and modernisation.

Synpromics to develop synthetic promotors for GE’s CHO platform

04-Jan-2017 - GE Healthcare hopes to increase the yield of biopharmaceuticals made using its Chinese Hamster Ovary (CHO) expression system through a partnership with synthetic biology firm Synpromics.

Wacker adding cysteine capacity through Spanish acquisition

21-Dec-2016 - Wacker says it is buying a large-scale fermentation facility in Spain to support growing demand for the amino acid cysteine.

Catalent’s CHO cell lines and Gate’s Foundation to make PATH Malaria vaccine

21-Dec-2016 - Catalent has partnered with US non-profit PATH for antibody discovery using the CDMO’s GPEx cell line platform, funded by PATH’s Malaria Vaccine Initiative (MVI).

Oxford genetics secures $2m for bioproduction optimisation R&D

21-Dec-2016 - Oxford Genetics hopes to provide improved bioinformatics in order to optimise mammalian bioproduction through a £1.6m grant.

Key Industry Events

 

Access all events listing

Our events, Shows & Conferences...